Accurately recommending items of interests is essential for users to improve their experience. To acquire better performance, a recommender system can utilize multiple sources of data and the social knowledge graph. This can lead to efficient use of information to improve the recommender system. By exploring the data and extract crucial features to feed to […]

Surgical Safety Technologies aims to provide healthcare professionals with the opportunity to perform research in areas of surgical performance and education and implement evidence-based solutions to improve patient safety. Search on video content would an ideal functionality to assist with healthcare professionals’ research. This project uses computer vision model to rank the relevance of the […]

Many retailers are interested in forecasting demand for the products they sell. Deloitte has used machine learning methods to tackle this problem in the past. However, this requires the creation of hand-crafted features based on product sales data, which is a costly and time-intensive process. Using alternative models to perform this task would remove the […]

Everyday millions of customers move through the sales cycles of companies, generating numerous data for potential use. The main objective of the research project is to advance the current state of the art techniques inside the company, with respect to the application of new algorithms on customer behavior data. From a research perspective, access to […]

Acknowledging that discrimination and prejudice of various sorts (e.g., verbal, behavioural, environmental) continue to exist in the education system, this research seeks to address how and why microaggressions against Black, Indigenous, and People of Colour (BIPOC), within engineering departments, show up among peers in classrooms, across interactions in lab environments, group-activities, and more. This research […]

Dopamine and noradrenaline are neurotransmitters that are released from neurons located in the substantia nigra and locus coeruleus. Therefore, these brain structures have the unique property of containing high concentrations of neuromelanin, a dark pigment that can be visualized with specialized MRI sequences. The neuromelanin-sensitive MRI signal has been used to visualize degeneration of these […]

Cerebral aneurysm (CA), is an abnormal dilation of the cerebral arterial wall, which accounts for more than half a million deaths each year worldwide. Flow diverters (FDs) represent one method recently developed in treating CAs. Typically, they do not need coiling (releasing platinum micro-coils within the aneurysm) and act purely to prevent substantial blood inflow […]

Ribosome biosynthesis is one of the most multifaceted and energy-demanding processes in biology. It involves over 250 factors that transiently associate with the nascent pre-ribosome in a well-orchestrated manner. Importantly, increased ribosome biogenesis has a critical role in cancer initiation and progression. Owing to the advances in cryo-electron microscopy, this pathway’s detailed mechanism started to […]

Heat management in semiconducting nanomaterials requires the design of engineered artificial structures, known as metamaterials, where thermal properties can be tuned almost at will by microstructural modifications. Testing a broad range of nanostructures for the particular device applications, with predictive behavior, is a grand challenge especially because of the difficulties associated with the experimental synthesis […]

The COVID-19 pandemic has illustrated the need for the development and commercialization of enhanced personal protective products, air filtration systems, and high-touch surface coatings which supplant residual disinfection and render viruses inert. The pandemic has also highlighted the need for local supply-chain establishment, including antiviral coating manufacturing and materials sourcing in Canada. This proposal is […]

In Canada, over 30% of adults and 10% of children are affected with non-alcoholic fatty liver disease (NAFLD), a chronic condition often related to obesity. NAFLD refers to a range of conditions related to excess fat in the liver, unrelated to alcohol intake. NAFLD is a precursor to liver cirrhosis, end stage liver disease and […]

Prostaglandin E2 stimulates bone formation in vivo and exerts its effects through the EP4 receptor. Unfortunately prostaglandin E2 and agonists for the EP4 receptor also cause unacceptable systemic side effects which have limited their clinical use as anabolic agents. We developed novel bone-targeting prodrugs that can deliver EP4 agonists selectively to bone and liberate active […]