Towards development of a biodegradable polymer for use in single-use surgical gloves

The proposed university-industry research aims to develop a biodegradable polymer with a target application in personal protective equipment (PPE), aligned with the ongoing global research efforts towards Next Generation Plastics (NGPs). The new NGP is expected to fully degrade within 2-5 years when disposed in soil and exposed to a combination of water, UV and […]

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Evaluation of PLO Micelles for Transdermal Peptide Delivery to Superficial Bone

This research aims to develop and test a transdermal delivery system for small bone healing peptide hormones. Peptides and many drug molecules do not usually penetrate the outer skin barrier, the stratum corneum, in order to treat the underlying body tissues. However, by using liposomal gel as a drug delivery medium, it is often possible […]

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Cytology-based DNA measurement for oral cancer screening

Oral cancer (OC) presents a global burden on society and the healthcare system with high incidence rates and poor prognosis. Despite the oral cavity being easily accessible for visual assessment, lesions are often detected at an advanced stage when the prognosis is poor and radical interventions are necessary. An invasive biopsy of a clinically suspicious […]

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Betulinic acid derivatives as a new agents for pediatric cancers

The aim of the project is to design and test different chemical derivatives of betulinic acid as a treatment for cancer. It is well known that betulinic acid is able to specifically kill cancer cells, and so we have developed several derivatives to improve biochemical properties such as solubility or biodistribution but maintaining the toxicity […]

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Practical implementation of an anisotropic rock mass strength model for rock slope stability analysis

As mine pit slope become higher, the implications of accurately predicted slope angles becomes greater for worker safety, environmental impact and economics. Over the past decade, data analysis and computational methods have resulted in significant research developments in this area. Utilizing these some of thee methods requires a high level of field data and large […]

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Establishing productivities of violacein production in recombinant E.coli using CSTR batch processing

Material Futures Inc. has developed a bioprocess to manufacture coloured pigments using cells, instead of petroleum. The process is carbon neutral, renewable, and has the potential to eliminate water pollution resulting from current dyeing methods. Working with students at the University of Waterloo, Material Futures Inc. will be scaling their bioprocess while exposing students to […]

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Genes to affordable medicines – Stream 1-A2

The Structural Genomics Consortium (SGC) is a not-for-profit public-private partnership research organization that aims to accelerate the discovery of new medicines through open science. This Mitacs cluster will bring together SGC’s industry and academic collaborators to work together towards new and affordable medicines for challenging diseases. Sixty-three post-doctoral fellows will spend 2-3 years developing open […]

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Development and Optimization of a Multiple Slice Cardiac Dynamic Contrast Enhanced MRI Method for Monitoring Perfusion within Infarcted Tissue

Each year approximately two out of every 1,000 Canadians experiences a heart attack. These patients are at increased risk for heart failure, a serious condition in which the heart cannot pump enough blood to meet the body’s needs. Heart inflammation that lasts too long following a heart attack may increase the risk of heart failure. […]

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Développement d’un algorithme de reconnaissance d’images de papillons tropicaux

Le nombre d’espèces qui nous entourent est si important qu’il peut être ardu, même pour les spécialistes, de toutes les identifier. Cela est particulièrement vrai pour les insectes. De plus, avec l’avènement des technologies mobiles de l’information, la quantité et la qualité des images disponibles n’a jamais été aussi importante. Grâce aux appareils photos numérique […]

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Development of Nickel-Rich and Lithium-Rich Layered Cathode Materials for High-Performance All-Solid-State Pouch Cells

This project will aim at developing all-solid-state pouch cells (ASSPCs) based on atomic layer deposition (ALD) derived cathode surface modification, ultrathin solid-state electrolyte sheets (USESs) and flexible electrodes preparation. The project includes: (1) fabricating uniform surface coating and doping on nickel-rich and lithium-rich layered cathode materials by ALD and post-annealing treatment, (2) developing sulfide and […]

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