Defining epigenetic drivers of primary and metastatic medulloblastoma – Year two

Medulloblastoma (MB) is the most common childhood brain cancer. Current treatment for these tumors is invasive involving irradiation of the entire brain and spine. Although some types of MB respond well, others have an abysmal prognosis, and the lack of less invasive therapies means that children undergoing treatment suffer from severe developmental defects and reduced […]

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Development of an advanced Control Strategy for chemical dosing in sewers

The process of chemical dosing in sewers for mitigating the effects of odor nuisance and corrosion needs a lot of improvement in terms of on-line control of the variable amount of buffered iron salt that needs to be applied for different operating conditions and different sewage flowrates. In order to achieve this goal, this project […]

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Simultaneous localization and mapping using a magnetic quantum sensor

Vehicles that are able to autonomously move in the air, on the ground, or underwater must fuse various forms of sensor data together in order to ascertain the vehicles location relative to objects or a map. Typical sensor data includes inertial measurement unit data and some sort of positioning data, such as GPS data. However, […]

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Building Performance Evaluation of Leading Energy Efficient Homes in Southern Ontario

The focus of this project is on building performance evaluation (BPE) in residential houses in Southern Ontario. Eight green homes will undergo BPE to see how well they are performing. The project will compare current building performance to the designed building performance. This comparison can help to see whether a “performance gap” exists. A performance […]

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Developing an interfacing platform technology for silicon-micromachined JFET biosensors

Biosensors are can detect a variety of molecules in a rapid and highly sensitive manner. A new biosensing technology was developed to allow scientists to customize the biomolecular target they wanted to detect, called an open-gated silicon junction field effect transistor (JFET). However, this technology lacks user friendly packaging needed accommodate its use in diverse […]

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Size Spectra Modeling to Assess Productivity, Recovery, and Sustainable Levels of Community Harvesting of Eastern Canadian Marine Shelf Ecosystems

Off the east coast of Canada we observe some marine ecosystems that are still recovering from prior overexploitation, such as the Newfoundland sh elf, while other regions have witnessed recent expansion of fishing industries, such as the waters off of Nunavut. This project seeks to analyze trends in overall ecosystem health and to assess the […]

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Complex Gill Disease Initiative

Complex gill disease affects millions of farmed Atlantic salmon on the Pacific coast of North America, each year. This disease results in hundreds of millions of dollaras in lost revenue for the industry, yet there are few tools for early diagnosis of the disease/syndrome and no current treatment/intervention strategies that work to control it. The […]

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Exploring perceptions on the QUIT smartcase to guide continued development of this digitally enhanced technology for reducing and quitting dependence on e-cigarettes.

There is growing evidence that e-cigarettes, also known as vaping, have led to an upsurge health risk to young people in Canada, including long-term harm to brain development and respiratory health. Due to such adverse effects, more and more young people indicate a desire to quit. However, such desires often become unsuccessful due to the […]

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Implementation of Photonic Computing Chip (IPCC)

The IPCC project aims to utilize the advancements in lasers, optics and semiconductor fabrication facilities to deliver a computing chip that uses laser instead on electrical signals to perform computations. The new paradigm of computation execution allows computations to be performed much faster at lower energy consumption which directly leads to lower costs for computations. […]

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Plant growth response to growth promoting rhizobacteria

Numerous species of soil bacteria flourish in the rhizosphere of plants, which may grow in, on, or around plant tissues and stimulate plant growth by a plethora of mechanisms. These bacteria are collectively known as plant growth promoting rhizobacteria (PGPR). Bacillus velezensis is a PGPR that promotes plant growth, enhances drought stress tolerance, and suppresses […]

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Application of Light Detection and Ranging in Right-of-Way Management Program

Light detection and ranging (LiDAR) is a method that uses light in the form of a pulsed laser to measure variable distances. These pulses are combined with other data (Global Navigation Satellite System (GNSS) and inertial navigation system (INS)) to precisely obtain the position of points over the shape of the earth and its surface […]

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