E-commerce has evolved rapidly in recent decades resulted from globalization and international trade. The demand of online shopping is increasing every day, which has opened business opportunities to attract more costumers locally and globally. However, achieving satisfactory user experience in online shopping remains challenging compared to in-person walk-in shopping. Currently, customers have to input static […]

We are building a machine learning system to help clinical experts accurately label medical notes with diagnosis codes. This will make it faster and cheaper to train machine learning models to identify important codes, including those related to infectious diseases and COVID, in large amounts of medical notes.

N=209 Seriously ill patients with COVID-19 require ICU care, and have high rates of mortality, especially amongst patients with concurrent diseases such as high blood pressure. Recent clinical data demonstrate that disease progression is associated with an overwhelming, atypical cytokine response known as “Macrophage Activation Syndrome” (MAS). Macrophages are immune cells that can directly damage […]

The detection of SARS-CoV-2, the causative of COVID-19, is challenging because the used techniques, such as nucleic amplification, cannot detect a whole virus. Instead, it amplifies nucleic acids that can be fragmented with no information about the presence of an infectious virus. We propose to use a technology based on the use of a physic […]

Depuis plusieurs semaines, la COVID-19 bouleverse plusieurs aspects de la société, tels que les liens sociaux ou économiques. Parmi les nombreux secteurs affectés, le domaine de la culture est particulièrement touché au Québec et partout dans le monde. Par exemple, les regroupements tels que les festivals, expositions ou spectacles sont maintenant annulés. Cela pose donc […]

This research project will seek to explain differences among non-profit organizations in terms of their resilience to the crisis generated by the COVID 19 pandemic. By studying 10 firms that have exhibited strong resilience and then 10 similar firms that have struggled, we will seek to better understand what might account for stronger resilience in […]

COVID-19 results in an increased expression of certain cytokines (i.e. chemicals produced by the body in response to an infection) that may result in inflammation, leading to organ and tissue damage. Cannabidiol (CBD) and cannabigerol (CBG) have been shown to have anti-inflammatory activity. For example, CBD has been shown to reduce the expression of cytokines […]

The COVID-19 pandemic has had an unprecedented global effect. While social distancing and proper PPE can minimize the spread of the virus, at risk populations have remained vulnerable. With additional waves of infection are likely to occur, there is an urgent need for an innovative protective solution. In the current project, we will repurpose a […]

This Mitacs-NSERC COVID-19 joint initiative is to investigate the mechanism of COVID-19 inducing hyperinflammation and cytokine storm. COVID-19 infected cells cause injury that triggers immune cells to release inflammatory cytokines. The partnership with Encyt Technologies Inc. and PI will use established immune macrophage cell lines to identify the molecular mechanism of hyperinflammation induced by COVID-19 […]

In the project, we will use an advanced microscope instrument, called a focused ion beam, to capture 3-D datasets of a coronavirus analogue and SARS-CoV-2 infecting cells to understand its biomechanical relationship at the cellular level. The intern will work on sample preparation, imaging of infection and turning those images into a computerized model to […]

The novel SARS-Coronavirus-2 becomes activated and is infective after interacting with the human TMPRSS2 enzyme, as it primes the virus to enter and hijack lung cells for viral replication. By designing drugs using a strategy that has shown success in inhibiting enzymes structurally similar to TMPRSS2 and understanding the exact shape of this enzyme in […]

The rapid spread of COVID-19, associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is of tremendous global concern. There is an urgent need to expand the current diagnosis capacity and to develop effective home-usable tests, and simple ones that can be used at the primary point-of-care. Ideally, the test will be simple enough that […]