Development and Commercialization of Photoresponsive Red-Shifted Gene-Silencing Agents

We have a technology that can potentially inactivate a class of pharmaceuticals. Pharmaceutical side-effects can have a detrimental effect on the health and wellbeing of individuals. Pharmaceutical companies can suffer significant monetary loss when drug candidates do not pass clinical trials. Given that the pharmaceutical industry is a multibillion-dollar industry, we believe there is significant […]

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Portable Thermo-Photonic Device for On-Site Detection and Quantification of Cannabis Consumption

With recent changes in legalization of cannabis around the world, there is an urgent need for rapid, yet sensitive, screening devices for testing drivers and employees under the influence of cannabis at roadside and workplace, respectively. Oral fluid test strips have recently been explored for such application. While these strips offer simple and non-invasive detection […]

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The development of SARS-CoV-2 lateral flow strip using genetically engineered viral antigen

While various community transmission mitigation tactics are being employed in regions across Canada, including stay home mandates, bans on public congregations, and provincial lockdown, public health experts and scientists agree that widespread availability of testing for COVID-19 would aid efforts in more accurately tracking the virus’ spread. This project aims to develop a more sensitive […]

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Determining the antiviral properties and mechanism of actions of BOLD-100 against SARS-CoV-2 in 2D and 3D cell culture systems

BOLD-100 is a promising new clinical stage therapeutic, originally developed for the use as a cancer treatment. The mechanism of action for BOLD-100 suggests that this therapeutic might also protect against infections with viruses, including coronaviruses like SARS-COV-19. The purpose of this project is to test the antiviral efficacy of BOLD-100 against SARS·COV-19 in 20 […]

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Exploring and Improving Self-supervised Methods for Large-scale Video Recognition

With the advancement of modern technology, especially the increase in network speed, videos are taking more and more important places among media types. With vast potential applications, video recognition has received great attention. However, video recognition is a non-trivial task: a lot of training data are needed for complicated neural networks, but annotated data are […]

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Analysis of Business-to-Consumer (B2C) Text Conversations collected during a pandemic and the adaptation of TxtSquad’s Technology Platform for Community-based organizations and small businesses

Txt Squad’s mission is to help medium-to-large companies sell and service their products through text messaging which results in saved time, improved customer experience and increased sales. A company can manage their customer service communications with TxtSquad using a team-based approach with rich cell phone text functionality that connects them directly to customers, bypassing emails […]

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Low-order Model of Supersonic Fluidic Oscillator for Superplastic Forming

The Superplastic Forming process involves gas injection from a variable pressure supply, to form a heated metallic sheet into a complex automotive body panel shape onto the surface of a die. The current process involves excessive forming times which allow residual stresses to relax and avoid cracking and tearing. Research shows that pressure pulsations of […]

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Part 2 (extension): Long-term evaluation of corticosteroid-releasing formulations to suppress implant device- related foreign body reactions and fibrosis

Implanted medical devices have dramatically improved the lives of millions of patients worldwide. However, in many cases, the body’s immune system rejects these devices and encapsulates the implant in fibrous scar tissue. This reaction is most detrimental to sensors for continuous monitoring and treatment of chronic conditions such as diabetes and those of the central […]

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Consequence assessment of potential tailings storage facility failures within the Canadian context

Recent catastrophic tailings storage facility (TSF) failures have resulted in immense societal, environmental and economic losses. Currently, research on TSF risk is primarily focused on the technical reasons for failure or post-failure environmental damages. Furthermore, limited research explores the financial, environmental and social consequences of potential TSF failure within potential tailings inundation zones. This project […]

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