Development and Assessment of Vitamin-Enriched Granule Extracts from Egg Yolk

The chicken egg represents an excellent source of nutrients, and the composition of the egg yolk can further be enhanced through modifications to the laying hen diet. While enhanced shell eggs are primarily sold as specialty eggs, an opportunity exists to add further value through the use of novel extraction technologies. The proposed research project […]

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Impact of a cognitive intervention program for adults with traumatic brain injury (TBI)

Cognitive impairments are the most common long-term challenges after traumatic brain injury (TBI). There is very little research on interventions to improve cognitive function after brain injury. The goal of this project is to evaluate whether and how an intensive cognitive intervention program (Arrowsmith program) may stimulate positive changes in the brain. We have already […]

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Detection and characterization of biodegradable polymeric biomaterials

Biodegradable polymeric biomaterials have been used extensively for medical applications such as implants, drug/gene delivery, and scaffolds. To determine the end applications, the molecular characteristics of these polymeric biomaterials are important which must be characterized. The development of reliable and fast analytical tool to detect, separate and characterize polymeric biomaterials in medical devices and drug […]

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Nutritional and exercise recovery strategies to improve sports performance in young athletes – the need for protein

The purpose of this multi-project study is to investigate the effects of two different doses of protein supplementation following exercise training on muscle damage and inflammation, as well as on post-recovery exercise performance in young swimmers. Sub-project 1 examines whether whey protein supplementation following a training session enhances exercise performance and affects post-exercise muscle damage […]

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Enhancing performance in Canadian athletes: A novel and integrated approach to neurofeedback and heart rate variability biofeedback training in the daily training environment

Two essential factors of sport performance at the elite level of sport are the ability to focus on the correct aspects at the correct time while ignoring irrelevant distractions and effectively managing anxiety in the very stressful environment of a World Championship or an Olympic Games. The purpose of the proposed research is threefold: (a) […]

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Chromosome Engineering for Bioproducts from Methanotrophs – Year Two

Currently Metagenom Bio Inc. offers contract research services in environmental microbial species profiling. Applications for this service include the monitoring of biogas operations, greenhouses, and mining processes. Metagenom Bio wishes to offer solutions that use microbes to generate value-added products. Biogas reactors can break down waste products and produce methane, or natural gas. This methane […]

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Identification of transcription factors involved in cannabinoid biosynthesis and glandular trichome formation – Year two

As an important medicinal plant, Cannabis sativa produces bioactive molecules that provide symptom relief for conditions such as severe cancer pain, nausea and vomiting associated with chemotherapy. The cannabinoid biosynthetic pathway that generates bioactive molecules has been studied for over a decade. However, understanding of transcriptional regulators that control cannabinoid synthesis is fairly limited. The […]

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Mycobiota dysbiosis in colitis-associated colorectal cancer

A higher incidence of colon cancer is reported in populations consuming high amounts of red meat, as well as in patients with inflammatory bowel disease, where gut bacteria participate in the development of inflammation. We found that dietary supplementation with heme, an element found at high levels in blood, is detrimental to gut health and […]

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Immune modulation with checkpoint inhibitor antibodies targeting GITR or OX40 to improve cancer immune therapy with DepoVaxTM vaccine and metronomic cyclophosphamide

Immunovaccine Inc. is developing immune therapies for cancer using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation provides controlled and prolonged exposure of antigens and adjuvants to the immune system, resulting in a strong, specific and sustained immune response. Immunovaccine’s translational research team is focused on improving responses in advanced cancers by combining […]

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