Application of advance signal and image processing to develop objective diagnostic and monitoring technologies as well as predicting the response to treatment for Alzheimer’s disease

An ongoing study in Winnipeg is investigating the possibility of using repetitive transcranial magnetic stimulation to help treat the cognitive and memory declines in Alzheimer’s disease. The objective of this project is to analyze in detail the current results of this study. We will look for connections between MRI scans of the participants and their […]

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Neuroimaging biomarkers of Parkinson’s disease identified through brain, brainstem and spinal cord imaging

In the current functional and structural neuroimaging project, we aim to identify functional and structural changes that correlate with disease presence and its severity  staging) and that can serve as a basis for future development of PD neuroimaging biomarkers. To achieve this objective we will use our expertise in functional neuroimaging of the cervical spinal cord (CSC), brainstem […]

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A cloud?based, multi?modal, cognitive ophthalmic imaging platform for enhanced clinical trial design and personalized medicine in blinding eye disease

Age Related Macular Degeneration is the leading cause of irreversible blindness in Canada and the industrialized world, yet there are no treatments for most patients. Tracery Ophthalmics has developed an imaging method, “AMD Imaging” (AMDI) that has generated unprecedented pictures of the retina (film of the eye) that include both known and unknown “flavours” of […]

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Preliminary Fall Detection/Prediction Data Science Project

Fall detection systems, are targeted to older adults living alone to identify fall events and mitigate prolonged wait times to treat injuries typically. These systems use a wearable, such as a Ffitbit or Apple watch, paired with an algorithm to detect falls and alert caregivers or emergency services. However, large variability in type and circumstances […]

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Design and Prototype Validation of a Bioabsorbable Flow Diverting Stent

An aneurysm is a balloon off a blood vessel in the brain, that could potentially bleed resulting in devastating consequences for the patient. Brain aneurysms a common, and are present in up to 7% of the general population. Traditional treatment of complex brain aneurysms involves placing a metal “flow-diverting” stent across the neck of the […]

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Identification of blood-based biomarkers predictive of pulmonary exacerbations in cystic fibrosis

Individuals with cystic fibrosis experience recurrent episodes of worsen in respiratory symptoms, termed pulmonary exacerbations (PEx). Early identification of individuals who are at elevated risk of PEx can improve their clinical outcomes and rescue their lung function. In this project, we will collaborate with the Prevention of Organ Failure Centre of Excellence (PROOF) to develop […]

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Molecular signatures and predictive biomarkers for phenotyping allergic rhinitis responses

Allergic rhinitis (AR) is in inflammatory disease characterized by nasal symptoms. It affects 20-25% of Canadians and is recognized as the most common allergic disorder worldwide. Patients can experience one of several types of responses to allergen onset hence a key hurdle to developing effective treatment plans is accurate diagnosis. The allergic responses are characterized […]

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RALI-DX: Rapid Diagnostic Tools for Acute Lung Injury

Sepsis, severe pneumonia and respiratory viruses are key causes of Acute Respiratory Distress Syndrome (ARDS)—a detrimental lung condition that results in >3 million ICU admissions/year and can lead to organ failure and death. In Canada, ~18,000 patients with ARDS are admitted to hospital annually and those requiring critical care place an immense burden on hospital […]

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