Biomechanical and Clinical Evaluation of the Levitation Knee Brace

Osteoarthritis (OA) is a debilitating musculoskeletal disease affecting approximately 1/3 of Canadians over the age of 25. Knee braces are often prescribed for OA patients to restore joint function and reduce pain in an attempt to avoid or delay knee replacement surgery. Most braces are designed to offload one side of the knee, however, more […]

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Transformation of THC and CBD synthesis genes into Yeast

Cannabinoids are diverse chemical compounds that are created by the Cannabis crop. To produce and extract the necessary amounts of cannabinoids for the market is taxing on the environment due to its high energy input costs. However, through the use of synthetic biology and genetic engineering, cannabis related chemicals can be created using simple yeast […]

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A humane pigeon management plan for TransLink: the case of Ovocontrol P

Pigeons can act as pests for the ability to spread disease as well as ruin infrastructure with their excrement. At Skytrain stations, they cause delays by triggering intrusion alarms as well as erode infrastructure. By attempting to reduce population numbers using a type of avian reproductive control that does not effect the environment or other […]

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Improved Yield of Poly-4-Hydroxybutyrate Bioplastic via Genetic Modification in R. eutropha

Plastics are the prime contributor to the global litter crisis. Every second, a quarter tonne of non-degradable plastics enter the world’s oceans. Despite this, petroleum-based plastic production continues to increase, with more than 300 billion kilograms of virgin plastic produced annually. Our team is slightly altering the metabolism of a strain of bacteria to efficiently […]

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Next-generation sequencing for the analysis of antibody development in vaccinated rabbits (Oryctolagus cuniculus) and in a humanized rat (Rattus norvegicus OmniRat) model.

ImmunoPrecise antibodies is a company that specialized in the production of custom antibodies, the Y-shaped molecules produced by living things to defend itself from infection. Their ability to recognize and bind to specific targets allows for their use in diverse scientific analyses where their specificity of binding is manipulated to allow for localization and/or isolation […]

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Chemical Genomic Analysis of the Mode of Action of Novel Boron-Containing Antifungal Agents for Crop Protection

Fungal pathogens of agriculturally significant crops pose a serious threat against global food security. This is exacerbated by the limited classes of fungicides that are commercially available for the farmers and the rapid emergence of resistance against the existing fungicides. Furthermore, resistance against agricultural fungicides can poses serious threat to human health as it can […]

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Determining position, speed and stride length using machine learning with sensor fusion based on ultrawideband local positioning system technology

Sensors that track human movement are becoming more and more popular in all kinds of applications including healthcare, sport and general human movement. However, traditional sensors generally have problems tracking individuals indoors and they are not very accurate when measuring subtle movements. Using innovative technology, new wearable sensors have been developed to track human movement […]

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Development & Benchtop Testing of Minimally Invasive Surgical Device

Xpan Inc. is developing a patent-pending expandable laparoscopic access port device. Xpan needs to develop its proof of concept prototype into a high-fidelity prototype through a series of iterative design, prototyping and benchtop testing. Research must be performed to select appropriate biocompatible material that achieve user requirements. Research must also be performed to evaluate the […]

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Generation and characterization of novel small molecule protein degraders in oncology

Many patients who initially respond well to highly efficacious chemotherapy eventually develop resistance and relapse despite continued treatment. These cancers acquire drug resistance to current therapies through various mechanisms such as the acquisition of mutations for example. Furthermore, some promising targets that play a crucial role in the progression of cancer have been deemed undruggable […]

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Integration of benchtop focused ultrasound device with a collaborative software platform for image-guided exploration and user-centred design guidelines

Focused Ultrasound (FUS) is a therapeutic modality that can concentrate non-invasively mechanical energy far from its source in just a few cubic millimeters. FUS is used, by example, to treat brain disorders such as essential tremor. At research level, very diverse approaches are being explored. From the treatment of Alzheimer Disease, brain stimulation with FUS […]

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