Development of a novel system to isolate vocal sources in crowded environments for individuals suffering from hearing deficits

Hearing aids are a common form of treatment for individuals suffering from a hearing impairment [1]. These devices work by collecting sound from the surrounding environment and amplifying that sound in the patient’s ear to improve hearing [2]. These devices work well under most conditions however, in noisy settings such as a busy restaurant, hearing […]

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High Fidelity Mixed Reality Platform for Surgical Training and Pre-Operative Rehearsal

We intend to create a novel mixed physical and virtual environment for use in resident education and surgical pre-planning. Our goal is to improve patient safety and amplify training and planning regimes with technology adjunctive to classic apprenticeship or cadaver-based education. To achieve this, we propose the creation of a mixed simulation paradigm expanding on […]

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Use of Guide and Outfitter Knowledge and Sampling to Advance Wildlife Health Surveillance Systems

This research intends to work towards establishing essential baselines of health status and trends in the Northern Mountain Population (NMP) of woodland caribou in the Skeena region of northwestern British Columbia. We will use scientific data from a guide and outfitter-led sampling program in combination with local ecological knowledge from practicing guides and outfitters in […]

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Action Research on Youth Physical Literacy in Recreation

Physical literacy means developing the foundational skills and the confidence required to participate in regular physical activity, play a sport or get to the podium. Research shows that physical activity levels start to decline as children enter into adolescence. Recreation organizations, such as YMCA Calgary are interested in finding out how their programs help support […]

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Using bioelectrochemical approaches to study microbes associated with oil and gas operations

Microbial activities in oil and gas operations can be beneficial or detrimental which economically impact the energy industry. Microorganisms can be responsible for souring and microbiologically influenced corrosion which damage oil and gas infrastructure, but they can also play a beneficial role in enhancing energy production, recovering chemicals from waste streams, bioremediation, and biofuel production. […]

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Activity-based screening of DNA-Encoded libraries

Cell surface receptors are targets of ~50% of pharmaceutical and biological drugs. Still many of such receptors have no known therapeutic inhibitors because 1) the receptors are only active in cells 2) isolation and purification of the receptor is not viable and 3) determining activity of a potential therapeutic is complicated by binding that can […]

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Fruit Extract to Dyes – Elucidating the Mechanism of Dye Formation using Genipin to Unlock New Colours

Dyes which are either sourced directly or derived from naturally-occurring products are of growing interest in the cosmetics industry. Sourcing chemical dyes or their close precursors from natural products can significantly reduce the environmental impact of manufacture by reducing the number of derivatization and purification steps. The industrial partner, Inkbox Ink, currently uses genipin, a […]

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Identification of heterotic gene pools to accelerate hybrid breeding in Brassica napus (canola)

Heterosis is a natural phenomenon where offspring (hybrids) outperform their parents in many agronomic traits, although exploited in breeding the mechanisms controlling heterosis remain elusive. Genetic distance between parents has been positively correlated with heterosis, yet does not adequately explain the phenomenon. Dividing lines from any crop into heterotic groups that provide optimal combining ability […]

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A novel home cage testing environment for frontal cortical neuronal recording in marmosets – Year two

Marmosets are a valuable model for investigating the neural bases of behaviour and cognition, and there has been a substantial increase in marmoset use in translational neuroscience research over the last few years. A comfortable environment is critical for marmoset neurophysiological testing. At Rogue Research the fellow will be involved in developing a unique apparatus […]

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Development of miniature fluorescence microscope with optogenetically synchronized patterned illumination – Year two

We propose development of miniature fluorescent microscope with flexible spatiotemporal photostimulation patterns of ensembles of neurons in freely behaving animals.For precision and targeted photostimulation of light-activated proteins (opsins), the light beam from high power incoherent light source will be shaped by user-controlled digital micromirror device (DMD). The light patterns formed by DMD will be sent […]

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Investigating the cell biology of cannabinoid synthesis in Cannabis sativa

Cannabis sativa is a plant well-known for its production of cannabinoids, which are lipids with unique pharmacological properties. These compounds are produced mainly in female floral buds in specialized epidermal outgrowths known as glandular trichomes. These structures consist of a long stalk supporting a disk of biosynthetically active cells that produce the cannabinoids. Cannabinoid biosynthesis […]

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