Many genes are implicated in the development and progression of breast cancer. One of these genes, mammaglobin 1 (MGB1), is specifically found in breast cells. MGB1 is routinely used for the detection of invasive breast cancer that migrate to distant organs of the body and form a secondary tumor. However, the specific role of MGB1 […]

Recent scientific breakthroughs have led to the development of methods to differentiate human PSCs (hPSCs) into skeletal muscle cells. This has allowed, for the first time, the development of cellular models to study muscle diseases such as Duchenne Muscular Dystrophy and the possibility to utilize these cells for cell therapy applications. However, the reliability, efficiency […]

There is an increase in brain diseases like Alzheimer’s and Parkinson’s diseases as the number of aged individuals is increasing. Currently there is no treatment available that can halt the progression of these diseases. Previous work has shown that a natural compound CoQ10 can prevent brain cell death. Similarly an Ayurvedic Herbal extract, Ashwagandh Root […]

Admittance in an animal shelter is often an intensely stressful experience for cats, leading to serious health and behaviour consequences impacting their welfare and adoptability. Recognizing, understanding, and minimizing factors that contribute to cat stress in shelters is an identified priority and ongoing challenge for shelter managers worldwide. A suitable acoustic environment is necessary to […]

Triozan™ is a safe, biodegradable and biocompatible hydrophilic and highly quaternized biopolymer with advantageous physicochemical properties that enables an efficient encapsulation and protection of drug molecules against degradation while simultaneously maintaining therapeutic integrity. We propose to encapsulate three drug candidates into nanogels formed from Triozan to enhance their therapeutic application and overcome multiple barriers such […]

Bats often use urban areas, but ecologists lack understanding of where they roost and forage. Bats are important predators on insect pests, including mosquitoes, so understanding their requirements is important. This need is made more critical by the likely imminent spread of an exotic fungal pathogen that causes white-nose syndrome, which is often lethal to […]

The American Black Duck is the most abundant breeding waterfowl species in New Brunswick (NB), and, although previously common throughout New Brunswick (NB), notable declines in breeding black duck abundance have been reported in the commercially forested area of NB in the last 20 years. In NB, forestry operations must maintain >=30m buffers around waterbodies. […]

The TransX Group of Companies is Canada’s largest privately owned transportation company. Its mission is to provide integrated transportation solutions to businesses throughout North America. In the fall of 2017, the Winnipeg office of TransX discovered that diesel fuel tanks for their long-haul refrigeration units contained a sludge-like, microbial biofilm and that the fuel filters […]

EMBERS Eastside Works (EW) is a new low barrier employment centre in the Downtown Eastside of Vancouver. EW helps people in the Downtown Eastside make connections to the world of work, earn income, and improve their livelihoods. The proposed research will work with EW to develop a database and information system that fits their needs, […]

Significant advances in technologies related to antibody discovery and development have allowed therapeutic antibodies to become the fastest growing class of biopharmaceuticals over the last 20 years. Northern Biologics is a biotechnology company that seeks to develop therapeutic antibodies for the treatment of cancer and fibrosis. Together with Dr. Jean-Philippe Julien at SickKids (University of […]

Vaccines are a vital part of society’s arsenal for preventing the spread of infectious diseases. Since they are challenging to produce, vaccine manufacturing is largely concentrated in select locations in the developed world. This situation presents steep obstacles to transporting them to people in the developing world who need them the most. Moreover, transportation and […]

Immunovaccine Inc. is developing cancer vaccines using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation that displays excellent tumor control and provides a long lasting and specific effect. The way by which this vaccine exerts its effect is unclear but the translational team at Immunovaccine is determined to discover its mechanism of action […]