Synchronization of ovulation to improve the efficiency of an in vitro embryo production/embryo transfer program in commercial operations in cattle – Year two

In vitro embryo production and embryo transfer (IVP/ET) is a technique that has been developed in cattle for genetic selection to enable rapid improvement in commercially important traits. Technological advances have resulted in a significant increase in the commercial use of IVP/ET in recent years, and have made this one of the fastest growing sectors […]

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A comparison of finite element model-predicted brainstem strains between injurious and non-injurious laboratory reconstructed football impacts

Studies of concussive events have shown that the response of the brain during an impact may not be the most reliable predictor of concussion, since the injury may be more closely related to the forces affecting the brainstem. A laboratory crash test protocol was developed to simulate player-to-player collisions in contact sports using crash test […]

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Testing, evaluation and development of a commercial protocol to differentiate hPSC-derived pancreatic progenitors into insulin-producing ?-cells in 2D monolayers and/or 3D culture systems

The generation of functional ?-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is a strongly investigated area. Recent scientific breakthroughs have enabled derivation of large quantities of human pancreatic ?-like cells in the laboratory, but the protocols are currently not consistent or optimized for cells of various […]

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The Effects of Mild Bilateral Jugular Vein Compression on Cerebrovascular Physiology

This project will investigate the effects of using the Q collar to apply gentle pressure to the jugular veins of the neck to monitor changes in brain (cerebrovascular) physiology during exercise and postural changes. Specifically we will investigate changes in brain blood flow velocity, relative changes in blood volume and oxygen levels, and changes in […]

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TRICHUM: Translating Research into Innovation for Cannabis Health at Université de Moncton

Supplying cannabis, and cannabis products, to a legalized retail market represents a major economic opportunity and has been identified as a growth opportunity under New Brunswick’s Economic Growth Plan (Province of New Brunswick, 2016). Indeed, the retail market value for recreational cannabis in Canada is expected to reach $8.7 billion annually (Deloitte, 2016); however, current […]

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Are bat boxes as artificial roost structures a threat mitigation tool or can they impede population recovery?

Bats are a crucial part of healthy ecosystems, providing vast economic benefits through control of forest, agricultural and human pest insects (including mosquitoes!). Unfortunately, bat populations face many threats, including an exotic fungus causing white-nose syndrome, which is lethal to bats. It is important to understand how we can enhance bat habitats so they can […]

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Altitude & Heat – environmental synergies to optimize human performance

The environmental stress of altitude and heat have both been shown to elicit divergent adaptive responses and are used by elite athletes to augment training adaptation and subsequent performance.   Indeed, 3-4 weeks at moderate altitudes can increase the body’s natural erythropoietin (EPO) responses, raising hemoglobin by 4-6% and enhancing endurance performance.  Conversely, as little as […]

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Ecology, Conservation and Welfare of Captive and Wild Animals

Animal welfare and behaviour is a concern in captivity but is also a factor affecting conservation success. An animal ability to cope with stressors, which varies between and within species, can affect survival of individuals and compromise a population’s viability. Human-induced stressors impact individuals differently depending on their personality, which applies to captive and wild […]

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Improved pulse pressure approximation and pattern recognition algorithm for prediction of blood pressure-related health issues

Continuous blood pressure (BP) monitor is highly beneficial for detection and prevention of stroke and cardiovascular disease. The most common BP monitor technique still relies on using a cuff that slows the blood flow, which is both uncomfortable and makes continuous monitoring impossible. Furthermore, research has shown that due to the numerous artifacts, the existing […]

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A Physiological Assessment of the Physical Demands of Riding a Snowmobile

The purpose of the present study is to scientifically evaluate the physical demand associated with the safe operation of a snowmobile under typical (normal) riding conditions experienced by North American snowmobilers. We will quantify the physical demand of snowmobile riding and compare this to national recommendations for the promotion of health and fitness, as well […]

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The development of monoclonal antibodies for early diagnosis and therapeutic application in Alzheimer’s disease

Alzheimer’s disease is the most common neurodegenerative disorder. The recent immunotherapy brings the hope of treating AD as suggested by several preclinical studies. This project first aims to develop a humanized monoclonal antibody to target the molecules involved in generating a toxic protein of AD, named amyloid ?, and test the application of this antibody […]

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