Self-powered microchips for rapid diagnosis and severity determination of urinary tract infections

Children presenting a fever without known sources are usually checked for bacterial urinary tract infection (UTI) which, in its more complicated forms, can result in permanent kidney damage. The gold standard conventional tests to diagnose complicated urinary tract infections are urine culture and kidney imaging with a radioactive tracer. However, these tests are lengthy (urine […]

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Development of Smart Socks To Prevent Diabetic Foot Ulcers

Diabetic patients suffer from reduced sensation in their foot which will be leading to foot ulcers that are hard to treat, and often resulting in limb amputation. The existing health-care techniques usually fail to prevent foot ulcers because they cannot monitor the foot in real-time. In this work, we seek to develop smart socks based […]

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Genetic profiling of disease progression in myeloma

The intern will be studying the way genetics are changed during the progression of multiple myeloma and cancers in general. The changes in the genetic profile will help understand the disease. Throughout the project, genetic alterations of chromosome ends, known as telomeres, will be analyzed through complex mathematical and computational 3D architectural softwares to predict […]

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Improved veterinary diagnostics for tapeworms

Dogs can be infected with several species of tapeworms, but show no obvious symptoms. Tapeworms are generally diagnosed by detection of microscopic eggs produced by the parasites that are passed in the dog’s stool. However, this technique is not ideal, as eggs are not always passed in stool, different tapeworms produce visually similar eggs, and […]

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Design and advancement of Graft Enabled Antibody Therapies (GrEAT) – Year 2

Membrane proteins such as ion channels, transporters or G-protein coupled receptors (GPCRs) are excellent but difficult drug targets involved in a large number of life-threatening diseases and conditions. These proteins, over-expressed and essential for disease onset and progression, are naturally targeted by toxins from venomous organisms. During evolution, these toxins have been optimized to efficiently […]

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Development of a simulation model for prediction of performance of a novel positive airway pressure (PAP) machine for treatment of sleep apnea

The gold standard of treatment for patients with sleep apnea are Positive-airway-pressure (PAP) machines. PAPs provide a one-size-fits-all solution of providing the same therapy in terms of airflow to every patient and every breath. This causes frustration and discomfort for patients, therefore patients don’t purchase PAPs or purchase and don’t use them; leading to 4 […]

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The use of whole-body kinematic technology for optimizing current steering deep brain stimulation in Parkinson’s disease patients

Patients with advanced Parkinson’s disease (PD) may develop motor complications caused by Levodopa, the current drug used for treatment. Deep brain stimulation (DBS) is an alternative surgical treatment where electrodes are implanted in a specific brain region to deliver current to surrounding brain tissue which helps to alleviate motor symptoms of PD. Presently, there is […]

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Development of Fungal-Specific Stress Response Inhibitors for the Treatment of Fungal Infections

Drug resistance of medically relevant microorganisms poses a grave threat to human health and has severe economic consequences. Fungal pathogens pose an additional complication as they are closely related to their human host. Current therapies to treat fungal infections are limited and drug resistance has already emerged in the clinic. We have conducted extensive research […]

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Exploring home range and habitat use during the breeding season of the Bicknell’s thrush (Catharus bicknelli) in New Brunswick Clear-cuts

The Bicknell’s thrush (Cathurs bicknelli) is a rare songbird with the most restrictive breeding range in North America. The Bicknell’s thrush spends its summer months breeding in high elevation, stunted growth forests – a habitat that the species specializes in. In New Brunswick, there has been a documented population decline of 11.5% per year since […]

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The effects of cannabinoids on vascular and cognitive function in young and old healthy adults

Cannabidiol (CBD) is a bioactive cannabinoid compound in marijuana (cannabis sativa), but unlike ?9 tetrahydrocannabinol (THC), lacks the psychoactivity effect of THC. Available evidence suggests that there are marked therapeutic CBD effects for diverse disease processes including inflammation, cancers, psychosis, and epileptic seizures. The purpose of this study, in both younger and older healthy humans, […]

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Plasma Surface Modification for Passive Microfluidic Immunoassays

Sensoreal’s patented technology allows them to perform complicated laboratory health testing procedures on a plastic microchip the same size as a credit card. The testing is done through the use of passive microfluidics, in much the same way as trees transport water to their leaves. A blood sample is placed in the loading port of […]

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