Optical Tissue Imaging DICOM/PACS Integration

The aim of this project is to research and develop a new DICOM modality for the optical coherence tomography images obtained by Perimeter’s Optical Tissue Imaging (OTISTM) device. Following the creation of a suitable modality, a novel solution for transfer to and integration with the PACS servers utilized by current Perimeter customers will also be […]

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Tissue Microstructure of Surgical Specimens depicted with Optical Coherence Tomography

Perimeter Medical Imaging (PMI) has developed an investigational imaging device to aid in achieving clear margins during surgical oncology procedures. This project will employ PMI’s device to image multiple types of human tissues, which have been previously removed during elective or medical procedures. This study will correlate the images obtained using PMI’s device with the […]

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Developing an On-field Test for Determining Recreational Water Quality

Recreational water sources are important commercial resources and activity hubs. Unfortunately, any public water source is prone to bacterial and viral contamination, which is a major concern for public health agencies. InnovoGENE Biosciences has a developed a simple test that can quickly determine the level of pathogens. Although this method has been rigorously tested in […]

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Material environments as metaphors: enhancing the well-being of people with dementia

The living environments have been increasingly considered as significant to the well-being of people with dementia in both research and practice. Addressing this, practitioners, including developers, operators, and architects who are in charge of the environmental creation of dementia care facilities, need to know the specific requirements of people with dementia, in order to apply […]

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Fine-scale habitat use by juvenile Chinook Salmon in the Salish Sea

Juvenile Pacific Salmon survival in the Salish Sea has declined dramatically since the 1980s. Our work is part of the Salish Sea Marine Survival Project (SSMSP), an initiative which seeks to understand this decline. We have been developing an economical, small vessel-based method to study how juvenile Chinook Salmon use their habitat in more detail […]

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SRRM4 protein purification and antibody production

The SRRM4 gene has been recently identified as a key protein responsible for a subtype of highly aggressive prostate cancers, called neuroendocrine prostate cancer (NEPC). Detection of SRRM4 protein in patient tumor biopsies is therefore important to predict and diagnose NEPC, so that early and more effective therapeutic means can be in place. Unfortunately, there […]

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Intertidal dynamics of First Nations’ clam beaches along a proposed liquefied natural gas (LNG) supertanker route

Proposed liquefied natural gas (LNG) developments in the traditional territory of the Kitsumkalum First Nations may have negative consequences for the productivity of local clam beaches resulting in decreased food security for coastal communities. This project will elucidate previously unknown community dynamics and environmental characteristics in clam beaches threatened by approved developments. This will increase […]

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Harnessing the power of horizontal gene transfer for yeast strain development

Yeast are used on a massive scale in many industrial settings, such as production of food and beverages, nutrient supplements, pharmaceuticals, and others, totaling over $5 billion dollars in annual market value. Most yeasts currently used for industrial purposes are taken directly from nature and not optimized for the specific process requirements of industry. Currently, […]

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Optimization of Dispersin B in Escherichia coli

Kane Biotech Inc. is a Manitoba based company that provides innovative technologies that breakdown and disperse microbial biofilms. Dispersin B is an enzyme that both inhibits and disperses bacterial biofilms. Kane Biotech Inc. has expressed this enzyme protein in E. coli, with the goal of developing Dispersin B based products. Dispersin B yield and cost […]

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Novel membrane mimetics in HT antibody screening and structural biology

Many therapeutic targets are proteins embedded in the membrane that surrounds the cell. Traditionally, such targets present major challenges, because they required the use of detergents to extract them from the membrane and to purify them. Such detergents can cause artefacts, hampering the development of novel therapeutics. Here we will test new methods that get […]

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SSI efficacy in treating infectious colitis

Inflammatory bowel disease (IBD) is a disease with unknown etiology that is characterized by uncontrolled intestinal inflammation and microbial dysbiosis. Qu Biologics’ Site Specific Immunomodulators (SSI) are a platform technology shown to improve the status of people living with IBD (Crohn’s disease and ulcerative colitis), with most of those patients showing clinical improvement also going […]

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