The present aim of this study is to use an infrared thermography technique to non-destructively measure the three-dimensional surface stress field in a synthetic femur fracture model repaired with a new composite plate vs a clinically-used metal plate. To this end, there are three main phases of this study. First, the infrared thermography system will […]

The brain is a dynamically evolving structure. Rehabilitation interventions take advantage of its malleable properties that persist even after an injury from stroke. Various interventions are used in clinical practice at an attempt to restore normal activity in the brain. Non-invasive brain stimulation is a novel technique that may act as a facilitator of brain […]

  Schizophrenia is a serious and severe mental disorder of yet unknown etiology. Genetic, developmental and environmental factors have all been implicated in the emergence of the disorder. In particular, abnormalities in both morphology and volume of the hippocampus have been implicated in the underlying mechanisms contributing to the emergence of psychosis in schizophrenia and […]

  Decreased brain volume in frontal regions is a prominent feature of chronic schizophrenia and has been linked to impairments in psychological functioning and social disability. These impairments persist over the lifespan, with approximately 64% of individuals experiencing severe social disability 15 years after first being diagnosed with the illness. Finding ways to overcome barriers […]

  Cancers are treated today with the appropriate combination of chemotherapy drugs, surgery and radiation. Chemotherapy is almost invariably dosed intravenously, and enters the systemic blood flow where it circulates around the whole body, coming into contact with healthy cells as well as cancerous ones. This systemic dosing has two big problems: too little drug […]

22q11.2 deletion syndrome (22qDS) affects 1/4,000 newborns. People with this condition can have various medical problems, and approximately 30% develop psychiatric illness such as bipolar disorder or schizophrenia. A recent study explored parents’ experience of receiving a diagnosis of 22qDS for their child. Families identified an unmet need for information from their healthcare providers about […]

  The cost and size of many imaging systems used in biomedical applications largely limit the possibility for longterm and imaging sessions in pre-clinical and clinical diagnosis. There is a need for low-cost imaging systems to map brain activity. Dr. Levi’s team has developed a unique miniature laser-based illumination system that enables novel optical imaging […]

  This research project will examine the imPROVE program at Provincial Health Services Authority (PHSA). The imPROVE program is a large scale initiative designed to ensure or improve the quality and efficiency of health service delivery using LEAN methodology. This research will investigate several components of interest as identified by key stakeholders, which will provide […]

Multiple antibiotic resistances have increased over the past decades, challenging our ability to treat bacterial infections and thwarting our ability to develop new antimicrobial agents. Many resistance genes have not evolved within the pathogenic isolates but were acquired by lateral transfer. We recently showed that genes conferring glycopeptide resistance are highly prevalent in the human […]

Medulloblastoma is the most common brain tumor in children. It is treated with a combination of surgical resection, chemotherapy and radiation. Radiation to a child’s brain can have harmful side effects that may have implications in later development. We intend to use molecular gene expression to classify archived tumors into 4 subgroups with associated low […]

Brain cancer is the second most prevalent cancer in children. Current treatment options are chemotherapy, radiation, and surgery, which either prolongs the child’s life for only two years or leaves them with negative side effects such as slowed development. Thus, there is a pressing need for new therapeutics. One of the focuses of our lab […]