Sexual offending is a major public health concern in our society, with 21% of those charged with sexual offenses being adolescents between 12 and 19 years. Characteristics of these youth include antisocial attitudes, and problems with self-regulation and intimacy, problems that interfere with learning, social maturation, and appreciating the rights of others. To date, […]

  I have recently developed a piece of software that can be used to interpret the effects of DNA sequence differences in human genomes. The analysis produces results that predict disease mutations. Dr. Rogan’s laboratory has developed approaches of visualizing DNA sequence data, which I will incorporate into this software. I will modify the existing […]

  A mathematical model is to be developed that describes how oxygen can move in a point-of-care blood gas sensor. The sensor measures the partial pressure of oxygen in a blood sample. Oxygen can move throughout the cartridge by diffusing through the various materials that make up the cartridge. The extent to which the oxygen […]

In Canada, 25,500 men will be diagnosed with prostate cancer in 2011, and 4,100 will die of the disease. New approaches are required to predict clinical outcome and personalized management of patients. Drs. Mai and Cayre will combine their two newly developed technologies and work towards obtaining a new solid biomarker that enables the assessment […]

  The problem of accurately predicting the onset of sustained postoperative atrial fibrillation (AF) in patients undergoing coronary artery bypass grafting (CABG) remains open. Investigators have reported many clinical indices currently associated with postoperative AF following CABG. Contemporary machine learning techniques are well-suited to recognizing underlying trends in 'training' data consisting of several labeled examples, […]

  The high throughput sequencing (HTS) platforms generate unprecedented amounts of data that introduce challenges in computational infrastructure. Data management, storage, and analysis become a major logistical undertaking for those adopting the new platforms. The requirement of large investments for this purpose almost signaled the end of the Sequence Read Archive hosted at the NCBI, […]

  Molecular profiles of tumour samples have been widely and successfully used for classification problems. A number of algorithms have been proposed to predict classes of tumor samples based on expression profiles with relatively high performance. However, prediction of response to cancer treatment has proved to be more challenging and novel approaches with improved generalizability […]

  Cerebral Palsy(CP) is a brain developmental disorder and a major cause of chronic childhood disability. It affects about 2 to 2.5 children per 1000 live births. Children with CP have varying symptoms affecting communication, health and specially mobility depending on the severity of the disorder. Children with severe CP usually have very limited mobility […]

  Obstructive sleep apnea (OSA) is a common respiratory disorder in adult population where it increases the mortality risk. The main treatment of OSA is continuous positive airway pressure and although it is effective in most cases, many cannot tolerate it. Therefore, it is important to develop new treatments for sleep apnea. We have proposed […]

  The intern will be assisting in the implementation of a research project that is intended to assess the effectiveness of two different smoking reduction/cessation interventions within a population of people with serious mental illness who are vulnerably housed or homeless. The partner agency, the Canadian Mental Health Association Ottawa Branch, is interested in the […]

  The Élisabeth Bruyère Research Institute is interested in addressing an organizational challenge associated with its size and the geographical location of its partners, which form a research community that is spread over multiple sites located in distant parts of the city. The large number of researchers and physical disconnection of the buildings limit social […]

  The goal of this internship is to support a project that NorDocs Technologies Inc. has undertaken to develop and improve a biomedical therapy device. This device contains a human-computer interface, and is smartphone-based. The device will be used for treating mild cognitive impairments resulting from an adverse response. An example of mild cognitive impairment […]