Electrophysiological studies of medical cannabinoids on 3D human cerebral organoids and neuroglial cultures

Epilepsy, characterized by recurrent seizures, affects 1% of the population. More than 30% of patients are drug-resistant, a significant burden to their lives. New innovative ways to treat the disorder are needed. Cannabidiol (CBD), a nonpsychoactive compound derived from the cannabis plant, has been shown to be a promising new treatment for epilepsy. In collaboration […]

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Structural and Thermal Analysis of an Insulated EPP Wall Panel System Design

Factory-built structural insulated panels are used for off-site building construction to minimize the labour needed for construction framing, which aims to save construction time and improve the quality of the installation. The panels, instead of using wood or steel framing, are the structural support for walls. Although the insulated panels provide structure, additional reinforcements are […]

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Evaluating the Impact of Cannabis Legalization in Canada on Risk-Taking Behaviours

The proposed research will focus on changes in cannabis use patterns and sources of supply following cannabis legalization, and on how these changes produce and/or reduce cannabis-related harm. The research will involve statistical analyses of Statistic Canada’s National Cannabis Survey (NCS). Some key areas of consideration will be: cannabis-impaired driving, cannabis dependence, and youth cannabis […]

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Antioxidants render silicone elastomer surfaces antiviral

Viruses are susceptible to antioxidants. COVID-19, to which the grant is directed, is also affected by surface active species, like soap. These two vulnerabilities of the virus will be combined to create silicone coatings that will render relevant surfaces anti-viral (e.g., doorknobs, facemasks and shields). Antioxidants will be modified with entities that allow them to […]

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Statistical perspectives on the use of pharmacovigilance data and electronic health records to verify predicted chemical hazards of drugs from in-vitro toxicological data

The liver is considered as one of the organs that are highly susceptible to drug-induced toxicity, leading to a diverse set of responses such as acute liver injuries, black-box warnings, and possible market withdrawal of medications in spite of having first appeared non-toxic and effective in animal and clinical studies. Over the last few decades, […]

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Designing Asymmetric structures to Generate Oblique Surf Waves in Rivers

Recreational river waves are gaining more and more popularity, but there is not enough academic research to support them and a few companies around the globe can artificially create them by adjustable structures in rivers. Surf Anywhere, the Calgary-based partner organization in this research, is one of those few companies which has completed and is […]

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Automated Generation and Integration of AUTOSAR RTE Configurations

Automotive Open System Architecture (AUTOSAR) is a system-level standard used worldwide by automotive companies and suppliers to develop standardized software development frameworks for automobiles. The RTE software of AUTOSAR should be configured to develop an Electronic Control Unit (ECU). The manual and semiautomatic code creation phases of the software development process for the RTE is […]

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Investigation of supportive policy for Active School Travel: Evidence-based recommendations for policies to promote active transportation for school journeys

Walking and wheeling to/from school represents an important source of physical activity for children. As policy decisions about how we build our neighbourhoods, schools, and transportation systems have changed, we have seen a worrisome decrease in the number of children who use active modes of travel to get to/from school. We have limited research mapping […]

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Examining the role for intimal cell communication in early atherosclerosis

Atherosclerosis is a disease defined by unresolved inflammation in the major arteries. High cholesterol is a major risk factor, resulting in fatty lesions developing silently for decades before causing heart attacks and strokes. Currently, no therapies exist that target the cells of the artery wall to suppress this disease. Myeloid cells (MCs) are white blood […]

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Vehicle Dynamics Modelling and Simulation for Use in the Development of a Self-Healing Auto Cyber Security System (SHACS) Proof-of-Concept

Vehicles rely on small computers located in various places. The electronic signals sent between these computers must be dependable. However, currently these signals can easily be hacked which threatens the vehicle and the people in and around it. A project is underway, involving Akimbo Technologies Inc., Solana Networks Inc., and the Carleton University Applied Dynamics […]

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Development of Lightweight Thermally Conductive Products Reinforced with Graphene Nanoplatelets for Automotive Industry

The focus of this project is replacing some of the current automotive parts by a stronger and lighter thermally-conductive polymer nanocomposite. This project takes advantage of the exceptional mechanical and thermal properties of graphene as a commercially viable and environmentally friendly nanomaterial, through an industrial scale process, i.e. injection molding. Therefore, the outcome of this […]

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