The interplay between mental health, mental illness, sport culture, and athletic performance in Olympic and Paralympic sport

Mental health is increasingly being recognized as a key component of elite athletes’ overall functioning and sport performance. Globally, research on antecedents (e.g., sport culture) and consequences (e.g., athletic performance) of mental health and illness in elite athlete populations is growing. However, little is known about the relationship between mental health, mental illness, sport culture, […]

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Bioorthogonal spin labeling approaches for high sensitivity electron paramagnetic resonance spectroscopy

In order to investigate proteins in their natural environment one can attach tiny reporter molecules to them that can be traced with appropriate instruments. However, these small reporter molecules may often cause strong perturbations to the functionality of the proteins, or cannot be seen due to experimental restrictions like low concentrations. Bioorthogonal chemistry aims to […]

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Cognitive Powertrain and Metaveillogrammetric sensing for transportation

There is massive growth in the area of smart cities (e.g. sensors in streetlights), smart cars, and “smart people” (sensors on people, e.g. wearable computing). In some cities like San Diego, there are cameras and microphones in nearly every streetlight in the downtown core area. Most cars made now have one or more cameras in […]

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The Role of Natural Background Radiation on Neurological Development and Processes

All species on the planet are affected by their environment: temperature, atmospheric pressure, daylight hours, and so on. These conditions affect how a species react to stress, grow, reproduce, and survive. Natural background radiation (NBR) is ever-present and has been prior to the evolution of all species. In order to study the effect of NBR […]

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Defining and Targeting Autoimmune Liver Disease

The liver is the largest solid organ in the body and is critical for metabolic and immune functions, however huge gaps still exist in our basic knowledge of the human liver. Due to challenges in obtaining human liver tissue and the fragility of liver specimens, little is known about the cells that make up the […]

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Accelerate development of new technologies and applications for advanced water treatment – Year 2

Global population growth, urbanization and changing climate patterns have increased the demand for potable water, wastewater reuse and value recovery from wastewater, and for remediation of industrial process water. Population growth also results in increased demand for the shipping of goods by ocean freight, with the associated risk of the transport of unwanted marine life […]

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Development of an antibacterial membrane for purification of floodwater

When floods happen, municipal water distribution systems are damaged and the residents will not have access to clean water. As a result, the will face the risk of health effects from water-born bacteria and pathogens increases. In this project, we proposed a system to purify the water stored frim flood water. This purified water can […]

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A mass balance modelling framework for chemicals and their primary metabolites for ecological and human health assessment – Year two

Chemicals manufactured and used in society degrade through physical and biological processes (e.g., photolysis, biotransformation) into break-down products (e.g., metabolites). Most “parent” chemicals can breakdown relatively quickly so that they are not persistent or bioaccumulative; however, some metabolites formed during the degradation processes can persist in the environment thus requiring consideration for ecological and human […]

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Development of a next-generation in vivo human gene-editing therapeutic platform – Year two

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

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Powered Hip Prosthesis

People with an amputation at the hip or pelvis have the most difficulty returning to walking because their artificial limb (prosthesis) must replace the hip, knee, and ankle joints. Current prosthetic hip technologies barely meet the person’s needs, leaving these amputees with few options. This project will build from current powered prosthetic knee technology (Össur […]

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Adsorbent screening for CO2, N2, and O2 for Landfill Gas separation by Adsorption

The proposed project would seek to develop a technology and identify adsorbents that are better able to remove impurities such as carbon dioxide (CO2), nitrogen (N2), and oxygen (O2) from biogas (mostly CH4, also referred to as natural gas) produced from landfills, using adsorption technology. Interns will be carrying out adsorbent screening, by determining kinetics […]

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