Medicinal Chemistry Studies on Small Molecule Glucocerebrosidase Inhibitors

The objective of this internship is to create new chemical compounds that can be used to further our research and understanding of a human enzyme known as GBA2 – implicated in several debilitating diseases and signalling pathways in the body. These compounds would not only serve as tools to probe GBA2 for additional information but […]

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Investigating the effect of the Virtual Meditative Walk on brain in chronic pain conditions: A longitudinal fMRI study

The Virtual Meditative Walk (VMW) (1) is a well-developed therapeutic protocol that can be used alone or in combination with the Mindfulness-Based Stress Reduction techniques in an Immersive Virtual Reality (IVR) environment. It has been shown to be effective in reducing pain levels in patients with chronic pain (CP); however, little is known about how […]

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Evaluation, optimization and modeling of sequencing batch reactors (SBR) operation for treatment of municipal wastewater

Sequencing batch reactor (SBR) is an activated sludge process that has been used successfully in municipal and industrial wastewater treatment. SBR process is operated in a batch mode where different batch phases run successively in a single tank or several tanks operating in parallel. Many studies on real-time control strategies have been employed to check […]

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Development of the early immune response assay in saliva

The current coronavirus outbreak highlights the importance of point-of-care (POC) rapid screening tools to identify and understand COVID-19 spread within the population. As countries work on flattening the disease curve, it is anticipated that billions of COVID-19 tests will be required for the next 12-24 months. Also, it is widely understood that the next pandemic […]

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Self-tuning servers within IBM cloud

Modern cloud-based applications are deployed as isolated processes in containers or virtual machines. These applications frequently require tuning by the application developer (or a DevOps engineer) in order to extract the requisite performance. For example, a Java application executing within a Docker container may have radically better performance if the host JVM runs with a […]

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A novel water-based air filtration technology using cryogel biomaterials

We have a new technology at the Heart Valve Performance Laboratory, University of British Columbia, Okanagan Campus, which can be used for the new generation of the facial mask. This biomaterial which is highly hydrophilic will be utilized for the construction of a water-based air-filter mask because it is practically 99% water and 1% polymer, […]

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Smart and Low-Cost Face-Shields Capable of Protection, Prevention and Detection for Essential Workers Fighting COVID-19 Pandemic

This project is in response to the COVID-19 pandemic and aims at developing a self-disinfecting personal protective equipment (PPE), such as goggles, and face shields, that are crucial to the safety of frontline workers. The low-cost, easy-to-implement fabricated end-product can be applied in both production and retrofit contexts. The approach embeds a thin layer of […]

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Computational Biochemistry Platform for Crop Health

The global population is rising, generating a need to produce more food to feed the world. Along with climate change, the food crops across the world are facing growing challenges from pests, pathogens and viruses that attack and destroy crops. In Canada, we export more than $7 billion worth of wheat every year. The Terramera-led […]

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BCCSA Silica Control Tool Gap Analysis

Inhalation of Respirable Crystalline Silica (RCS) generated during construction activities such as cutting or grinding can cause lung cancer and the irreversible lung disease. Exposure to RCS is common on construction sites because silica is a naturally occurring mineral that is present in many construction materials. The Silica Control Tool is a risk assessment tool […]

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