Development of a human immortalized FSHD cell line to study the epigenetic targeting of DUX4 to treat FSHD

Facioscapulohumeral muscular dystrophy (FSHD) is a debilitating disease resulting from the loss of skeletal muscles mainly in the face, shoulder blades and upper arms. FSHD results from expression of the protein DUX4 which causes skeletal muscle cell death and therefore loss of muscles. This project aims to immortalize isolated skeletal muscle cells from patients with […]

Read More