Metastatic tumors are a major concern in childhood cancer and the single most prominent cause of patient mortality. Metastasis is a complex process involving several cellular processes, each of which involves numerous extra and intracellular events. Therapeutic targeting strategies are hampered by a large degree of redundancy in the systems controlling metastatic behaviour and by […]

Medulloblastoma is the most common form of pediatric brain cancer with a five-year survival rate of approximately 70%, yet for some children’s survival is as low as 40%. Many of the treatment options for these patients may be effective in extending the five-year survival rate, however, quality of life issues still persist for these young […]