Chemicals manufactured and used in society degrade through physical and biological processes (e.g., photolysis, biotransformation) into break-down products (e.g., metabolites). Most “parent” chemicals can breakdown relatively quickly so that they are not persistent or bioaccumulative; however, some metabolites formed during the degradation processes can persist in the environment thus requiring consideration for ecological and human […]

Thousands of organic chemicals have been synthesized and commercialized for industrial and consumer uses. However, an increasing number of organic chemicals are revealed to be “hazardous” because of their potential adverse environmental and/or health effects. The project seeks to identify the primary route(s) that humans take up these organic substances, e.g., use of personal care […]

Society uses thousands of chemicals and the potential risks to humans and the environment for the vast majority of these chemicals are largely unknown. It is not feasible to measure all of the chemicals and there are substantial data gaps; therefore, models are required to screen and evaluate chemicals for potential exposures and risks to […]