Comparison of biological effects of Ceylon cinnamon water Extract and metformin

The use of cinnamon as a flavoring agent and a remedy for metabolic, respiratory, and gynecological disorders is widespread throughout the world. Studies suggest that Ceylon cinnamon may be useful in the treatment of type 2 diabetes. This project will use a high-throughput method to analyze how a concentrated water extract of Ceylon cinnamon changes […]

Read More
Thermal imaging for conservation and restoration success

Land surface temperature can tell us a lot about the health of ecosystems, forests and trees. Generally, the healthier, greener and more diverse a forest is, the colder it is, as plants use solar energy to grow, rather than releasing it as heat. This project focuses on using images of temperature measurements from satellites, space […]

Read More
Phytotechnologies Monitoring Impacts and Resilience of Native Species and Northern Climates

The Phytoremediation Pilot Project is a collaborative effort between Aya Kitchens and Landscape Architect Pete North to create a buffer system that will stabilize soil contamination left by historic industrial activity at 1551 Catepillar Rd., Mississauga. The site borders the Little Etobicoke Creek, a tributary to the Etobicoke Creek and designated a Significant Natural Area, […]

Read More
Synergistic Ionic Liquids – Chitin Nanowhiskers (CNWs) – Epoxy Nanocomposites for Improved Mechanical Properties

Chitin is an abundant resource in the form of shell waste from food industry in Canada and the world. BOCO Bio-Nanotechnologies has currently the infrastructure in place for scalable extraction of chitin nanowhiskers (CNWs) from crab shells. CNWs are the crystalline form of chitin molecules, possessing high strength, stiffness and aspect ratio, making them an […]

Read More
Optimisation of multistage mixer-settler solvent extraction process for the recovery of value metals in leaching of low-grade ores and secondary materials

The demand for elements such as nickel, cobalt, zinc and silver in various applications has increased significantly. Innovation to recover these elements now plays a major role in metallurgical processes as established technologies have challenges in treating available ores while meeting the increasingly stricter environmental regulations. Additionally, secondary sources have become a valuable resource that […]

Read More
Probiotics to prevent the Progression of Non-alcoholic Steatohepatitis to Cirrhosis

As a result of increasing obesity, non-alcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease. Non-alcoholic steatohepatitis (NASH) is the pathogenic form of NAFLD and can progress to cirrhosis and need for liver transplantation. There is currently no Health Canada-approved therapy for the treatment of NASH. The intestinal microbiome has been […]

Read More
Developing methods to isolate regulatory innate lymphocytes

Enhancing tissue homeostasis and immune tolerance mechanisms is pivotal for the development of new therapeutic approaches for transplantation and autoimmunity. This proposal is focused on harnessing newly discovered types of lymphocytes that regulates immune responses in cell-based immunotherapies. We are developing methods to isolate and expand these newly identified regulatory lymphocytes and are assessing their […]

Read More
Development of the library of nanoparticle contrast probes for tissue clearing 3D microscopy compatible with multi-modal imaging in fluorescence, dark field, MRI, CT and electron microscopy modalities

High resolution 3D microscopy is a rapidly growing area of biomedical research, which has high potential to replace traditional 2D histology used for the analysis of tissue biopsies of cancer and other diseases. However, currently there is a limited availability of contrast agents that can label organs, biological tissues, and cells in a live animal […]

Read More
Improved process modeling and optimization of the Birla Carbon Process

This project is a collaborative relationship between the Combustion Research Laboratory (CRL) at the University of Toronto and Birla Carbon. Birla Carbon is one of the largest manufacturers and suppliers of high quality carbon black additives globally. Carbon black has usage potential across an array of diverse application segments including rubber products, black pigment, UV […]

Read More
Machine learning in the operating room: focus, performance, and the medical record

This proposed study will significantly enhance our current understanding of how specific intra-operative factors can impact patient outcomes. Our proposed work will provide a proof of concept that machine learning can objectively predict a specific, high-impact post-operative complication, allowing us to move forward with scaling this work to a wide variety of surgical settings. Moreover, […]

Read More
Automated clinical note generation from clinician-patient dialogues

This project will investigate improvements to models for automatically generating physician notes from transcripts of conversations between physicians and patients. The model will capture important medical information such as symptoms, treatments, and medications, and automatically formulate a free-text note that mimics the style of the physician’s manually entered notes. The model will use context and […]

Read More