Osteoarthritis is a major obstacle to work productivity and quality of life for many Canadians, affecting over 10% of the general population and 15% of Saskatchewanians, with the elderly increasingly affected (>40% of Canadians over 65 years old). At the cellular and molecular level, osteoarthritis involves two main defects: 1) degradation of sugar-coated proteins (proteoglycans) […]
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