This project will profile the use of new drugs of rheumatoid arthritis, in a population-based sample. Potential differences in the use of these agents will be examined to identify discrepancies in drug use patterns across demographics, which could be addressed through targeted strategies. Our proposal is timely in terms of increasing attention on the part […]

The goal of the current research is to design an injectable polymer-lipid (Pol.i) formulation to treat ovarian cancer. The PoLi drug delivery system is a hiocompatible and biodegradable, physically cross-linked gel that has the potential to provide dramatic improvements in the treatment of ovarian cancer. It is formulated as an injectable gel (all components are […]

Stem cells are at the forefront of modern medicine and are expected to revolutionize both the human and veterinary healthcare industries. Currently, a major obstacle to the field is the time-consuming and costly technical time spent growing and maintaining various stem cell populations. The degree of contamination with non-stem cells, ability of the stem cells […]

  The purpose of this proposed research is to determine a mechanism (i.e. information posted on an appropriate website) to assist consumers with the selection of a vitamin/mineral supplement.  The principles to be considered are: appropriate dosage, product quality, high benefit, and low risk. The Dietitians of Canada have agreed to contribute funds for this […]

  Arthritis is a debilitating disorder characterized by chronic inflammation and persistent pain. This project aims to uncover ways of reducing the pain and discomfort felt by people afflicted by this disorder.  A number of key points will be addressed through this project. Firstly, we will gain a better understanding of the possible neurological component […]

Flavonoids are polyphenolic compounds which give fruits and vegetables their bright colours. Habitual consumption of dietary flavonoids reduces the risk for neurodegenerative disorders such as Parkinson’s disease, stroke and Alzheimer’s disease. Pre-clinical studies performed using animal models for these disorders have convincingly demonstrated that flavonoids not only halt the pathological processes which cause neurodegeneration but […]

The first successful clinical application of nanotechnology was the use of a nanoparticle container to deliver a drug to a tumour. That basic strategy of using a nanoparticle to carry a treatment or indicator molecule has a lot of potential, but requires continued research to determine the therapeutic effectiveness and potential toxicity of each container […]

Pharmaceutical platform technology (PPT) was invented by Sinoveda Inc., the partner organization, to accomplish the tasks of identification, purification, and activity determination for the active ingredients of natural herbal remedies, with the goal of developing and optimizing the remedies. However, two issues remain to be tackled in the PPT process: first, there is as yet […]

There is an increasing number and variety of calcium supplements being made available to the Canadian public, often making claims regarding improved action over competitor products. The purpose of this project is to evaluate the effects of drugs and nutraceuticals upon bone health, particularly if they contain elements (such as calcium) which incorporate into newly […]

The principal objective of this proposal is to discover novel drugs to treat colon cancers. Currently colon cancer is a huge medical problem and there are many disadvantages to current drug therapies. These disadvantages include their ineffectiveness to completely eradicate cancers, causing toxic side effects and the development of multidrug resistance. A group of compounds […]

Product quality is a factor in insuring business success and user satisfaction. It is acheived through vigilance within quality systems. This project will explore how quality-by-design can be supported through serial recording of material signatures extracted from image analysis of baked goods produced by the industrial partner TWI Foods. An innovative digital image recording system […]

The requirement for dissolution testing (both routine sample and method development) is increasing for all of the current and future programs at Accucaps and is a regulatory requirement for most oral pharmaceutical products. The need for access to capacity and development capabilities for dissolution must reach beyond Accucaps. For these reasons, a collaboration with Dr […]