Annually, 2 million individuals in North America suffer mild traumatic brain injury (mTBI) or concussion (cost: $75 billion), with 200,000 in Canada. An objective tool is required to distinguish concussed subjects acutely from ontrols, and to predict who will develop chronic symptoms. The frontal lobes, the corpus callosum, and the thalamus play key roles in […]

The purpose of the project is to assess the housing, community engagement, and social inclusion needs and challenges faced by different residents, many of whom are older adults and are residents in Brightside Community Housing Foundation. Also known as Brightside. A mixed method approach (dempgrahic questionnaire, survey and focus group) will be used in this […]

Cancer metastasis is responsible for 90% of cancer deaths. In metastasis, a group of cancer cells detach from the tumor, entre the blood stream and ultimately make new colonies in other organs. In this study we aim to develop a new technology to target these cancerous cells in the blood circulation with laser irradiation. We […]

Drugs that inhibit a protein’s function do so by binding that protein and blocking interfaces relevant to its activity. This requires drugs to have high affinities towards and to be in high excess of their targets. Another approach called Proteolysis targeting chimeras (PROTACs) can be used, which hijacks a cell’s protein-degradation pathway by linking an […]

The Canadian Association for Graduate Studies (CAGS) has created aTask Force on Truth and Reconciliation Calls to Action and Graduate Education (Reconciliation Task Force). This Reconciliation Task Force will examine the implications for graduate education in relation to the Truth and Reconciliation Commission of Canada’s (TRC) Calls to Action, to reflect on the role of […]

Pelvic organ prolapse (POP) is the descent of the pelvic organs into the vaginal canal, affecting up to 50% of the female population. Pessaries are intravaginal medical devices used to alleviate the symptoms of prolapse. However, pessaries are fit through trial and error and finding the right fit is not guaranteed for all patients. Cosm […]

This project will investigate whether playing an immersive virtual reality (VR) game called DoVille is beneficial to older adults’ memory and navigation abilities. Spatial navigation is a fundamental skill that relies on our ability to make an accurate mental map of the space around us, be aware of our position in the environment, and remember […]

Effective patient communication is challenging and obstacles such as health literacy, culture and language play a vital role in comprehension and can influence treatment outcomes. Tools to help healthcare professionals educate patients present limitations, particularly for patients with barriers to traditional teaching methods. Preoperative education helps patients to experience less anxiety, take an active role […]

An aneurysm is a balloon off a blood vessel in the brain, that could potentially bleed resulting in devastating consequences for the patient. Brain aneurysms a common, and are present in up to 7% of the general population. Traditional treatment of complex brain aneurysms involves placing a metal “flow-diverting” stent across the neck of the […]

Individuals with cystic fibrosis experience recurrent episodes of worsen in respiratory symptoms, termed pulmonary exacerbations (PEx). Early identification of individuals who are at elevated risk of PEx can improve their clinical outcomes and rescue their lung function. In this project, we will collaborate with the Prevention of Organ Failure Centre of Excellence (PROOF) to develop […]

There are 2.6 million Canadians with Chronic Obstructive Pulmonary Disease (COPD). COPD is a disease characterized by progressive loss of lung function that leads to shortness of breath, poor quality of life, reduced productivity, emergency visits, hospitalizations and mortality. The World Health Organization estimates that COPD will be the 3rd leading cause of death worldwide […]

Patients with inflammatory bowel disease (IBD) have an inflamed digestive tract and experience diarrhea, fatigue, and abdominal pain. Youth with IBD are six times more likely to take opioids than youth without IBD. We are currently in the midst of an opioid crisis. In 2016, there were almost 3000 deaths related to opioid use in […]