Manual Wheelchair Simulation with iDAPT’s CEAL Simulator

  The proposed MITACS project is intended to be a vital component of a manual wheelchair simulation project at Toronto Rehab’s CEAL Laboratory, which will re-create the experience of navigating the built environment with a wheelchair. Specifically, the internship will focus on the design and fabrication of a novel wheelchair interface that provides a person with force-feedback at […]

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Fluorescently-labeled nanoparticle target for imaging

  There is currently a great need to develop better imaging probes for studying biological process. In this proposed internship, Drs. Pacheco and Hashir will be evaluated an aluminum coated alloyed quantum dot system. These quantum dots are brighter than organic fluorophores and with the aluminum surface coating, these quantum dots are less pervious to environmental factors. This internship […]

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SN-38 (or 5-FU) drug encapsulation in liposomes transported by magnetotactic bacteria for localized colorectal cancer treatment

  Cancers are treated today with the appropriate combination of chemotherapy drugs, surgery and radiation. Chemotherapy is almost invariably dosed intravenously, and enters the systemic blood flow where it circulates around the whole body, coming into contact with healthy cells as well as cancerous ones. This systemic dosing has two big problems: too little drug […]

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Multimodal optical brain imaging for epilepsy applications

  The cost and size of many imaging systems used in biomedical applications largely limit the possibility for longterm and imaging sessions in pre-clinical and clinical diagnosis. There is a need for low-cost imaging systems to map brain activity. Dr. Levi’s team has developed a unique miniature laser-based illumination system that enables novel optical imaging […]

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Surgical simulator design and evaluation using game engine technology

Surgical training is increasingly being done using simulator technology in order to teach basic skills to residents without risking patients’ lives. However, neurosurgery lags behind other surgical specialties in the adoption of simulators. Since there are no commercial simulators in this domain, the National Research Council has embarked on a neurosurgery simulator development program, in […]

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Synchrotron imaging of ovaries ex Sstu

Conventional ultrasonography is limited in its ability to image small structures within the ovaries (eg. the eggs and surrounding cells, small fluid filled sacs that contain the eggs known as 'early antral follicles', the structure of the ovulation glands). Preliminary data obtained from our research team at the Canadian Light Source (CLS) have indicated that […]

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In-vitro simulation of fracture, wear, corrosion and distraction in total hip replacements

Reports of in vivo total hip replacement failures have raised concerns over their load bearing capacity, safety, reliability and service life particularly as hip arthroplasty is being extended to even younger patients. Therefore, it is crucial to ensure continual patient monitoring and develop proper testing standards. This study focuses on investigating retrievals and in vitro […]

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Low cost Microchip for Point of Care high Sensitive Assays

We have developed microfluidic polymer chips, and their associated reader for rapid differential diagnosis of disease states2. Each polymer chip is 2×2 cm2, and needs only 10 μl of whole blood sample of the patient for diagnoses. The turnaround time from introducing the blood sample to get the results is 15-30 min. The chip contains […]

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Improved inhibitors of HIV infection

ViroCarb has identified a new class of HIV inhibitors against a new therapeutic target on the HIV envelope protein gp120, present in all HIV, including drug resistant strains. The objective of this internship is to conduct screening studies of libraries, designed based on this new chemical class for optimal efficacy and drug-like properties, using methods […]

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Optimization of Graphical User Interface for the Digital Pathology Workstation

The workflow of pathologists will soon be revolutionized with the introduction of digital pathology allowing pathologists to view tissue samples as a digital image on a computer workstation. Such a conversion from traditional microscopy will bring many benefits to the pathologist’s workflow aiming to boost significant efficiency as well as ergonomic benefits. However, much work […]

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Growing Up With Cerebral Palsy: Transitioning from Childhood to Adolescence in the Healthcare System

Children living with NDDs are often dependent on their parents and healthcare providers. As these children reach adolescence and prepare to transition from the pediatric to the adult health care system many issues affecting their autonomy are currently not being addressed. In addition to feature articles, sidebar articles with multimedia components will further examine these […]

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