The proposed project will accelerate the drug development capabilities of 48Hour Discovery INC (48HD) to find high affinity drug candidates for treatment of COVID. The deliverable for this project will be high potential new drug candidates from 48HD’s drug discovery pipeline for COVID and other targets using unique molecular libraries of 48HD. The libraries are […]

Nuclear medical imaging relies on the detection of radiation that is emitted from the body after a radioactive isotope that has been fused to a disease targeting molecule (aka radiotracer) is administered to the patient. For example, positron emission tomography (PET) scans can be used to image and diagnose disease in the body with extremely […]

Organic contaminants enter the marine environment through atmospheric transport, runoff into waterways, or directed disposal into the ocean. They are prone to long-range, bioaccumulation and can have adverse effects on human health and the environment. In this project, a simple and convenient extraction device developed for analysis of organic pollutants will be examined for various […]

To combat the growing need for accessible freshwater sources across the globe, new technologies that don’t rely on fossil fuels are ideal. Additionally, these technologies should be easily implemented in the developing communities that need them most for lower cost than the current options. The purification of seawater, also known as desalination is a highly […]

The Canadian government has vowed to reduce their pollutant emissions by 2030 in order to curb the effects of climate change. This means that shipping companies must make strides to reduce their overall emissions. This project will use novel sponge-like frameworks, called metal-organic frameworks (MOFs), to remove environmentally toxic pollutants from exhaust gas. The materials […]

Urinary tract infections caused by indwelling catheters (CAUTIs) employed for the treatment of urinary flow are very common. Almost 100 million of these devices are sold on an annual basis with around 25% of these being marketed in the USA. In addition to the cost of catheters and their insertion, hospital treatment of CAUITs runs […]

The COVID-19 pandemic is caused by SARS-CoV2 coronavirus. This virus which infect cells that are vital in human organs leading to multiple diseases in need of timely medical treatment. There is a great need in search of inhibitors to block such viral infections as a means for disease prevention and/or treatment. Cannabinoids, such as cannabidiol […]

Due to the increased demand for isopropyl alcohol industrial clients are turning to replacements for industrial uses. Producing an alternative for isopropyl alcohol for specific industrial applications is now a sought-after target. Creating an environmentally friendly alternative is desired since volatile chemicals used in industrial applications are a major contributor to smog formation. To combat […]

Graphene is considered a strategic nanomaterial for the development of clean technologies due to its unique properties. According to Allied Market Research, the global graphene market was valued at US $91.3 million in 2019, and is projected to grow to US $1.4 billion by 2027 at a compound annual growth rate (CAGR) of 40.2% from […]

More than 2 million Canadians suffer from diabetes, a disease associated with the body’s inability to produce or effectively use insulin. The high blood sugar levels associated with diabetes can lead to serious complications such as vision loss, kidney failure, cardiovascular problems, and amputation. Therefore, diabetes patients are treated with insulin, with the aim of […]

Mental illness and addiction refer to a wide range of disorders that affects mood, behavior and thinking and thus leads to depression, anxiety disorders, substance use disorder and stress. The psychedelic drug assisted therapy functions as a mental health therapy, which is evolving at a quicker pace nowadays. These drugs are useful in the treatment […]

The current gold standard for the diagnosis of genetic disorders and infectious diseases involves the use of molecular methods for target gene detection through DNA/RNA amplification techniques. However, this requires a critical upstream step of extracting purified nucleic acid (NA) material from a variety of collected patient samples. This step can be easily performed through […]