UVPD of DMS-MS-selected SARS-CoV-2 peptides

Differential mobility spectrometry (DMS) is a technique that is used for the analysis of chemicals by separating complex gaseous mixtures under the influence of an electric field. It is a widely used technique and is successfully deployed in many areas, including drug and explosives testing at airports. In analytical laboratories, it can be used to […]

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Medicinal Chemistry Studies on Small Molecule Glucocerebrosidase Inhibitors

The objective of this internship is to create new chemical compounds that can be used to further our research and understanding of a human enzyme known as GBA2 – implicated in several debilitating diseases and signalling pathways in the body. These compounds would not only serve as tools to probe GBA2 for additional information but […]

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Direct Lithium Extraction (DLE) from brine solution using electrochemical method

The demand for lithium-ion batteries (LIBs) is on the rise, mainly due to increased interest in portable devices, electric vehicles and grid-storage applications. The key component in such rechargeable batteries is lithium, which is trivial from the name itself as well, as lithium-ions shuttle back and forth during charging/discharging process. Consequently, lithium production demand has […]

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Silicon Quantum Dot Trace Explosive Sensor – Year two

The rapid detection of high energy materials (i.e., explosives) and chemical, biological and radioactive (CBR) agents have received substantial attention because of its obvious importance to security and forensics. Applied Quantum Materials Inc. (AQM) is developing a straightforward luminescent quantum dot paper- and/or cloth-based detection system that shows instantaneous optical detection of nitro-based explosives in […]

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Nanostructured ceramic catalysts for fuel cells

Currently, burning fossil fuels such as coal, oil, and natural gas as a primary source of energy is a contributor to rising atmospheric carbon dioxide and climate change. Fuel cells are a promising environmentally friendly technology for sustainable clean energy, where the only byproduct is water. An important component of fuel cells for generating electricity […]

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Finding an optimized contact material for interconnect layers in reversible solid oxide fuel cells for the conversion of CO2 and H2O to syngas

SeeO2 Energy has developed world-leading catalysts for reversible solid oxide fuel cell (RSOFC) systems with promising performance to produce syngas from H2O:CO2 feeds. The company has scaled-up the technology and has moved closer towards commercialization by building larger cells. However, assembling the RSOFC stack presents challenges due to issues associated with contact materials especially at […]

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Synthesis and evaluation of Antibody conjugated to cyclical peptide toxin drug for the treatment of multi-drug resistant cancer cells

Antibody Drug Conjugates (ADC) are an emerging class of drugs that combine antibodies and a drug payload. The antibody cargoes the drug payload to specific targeted cells improving both safety and efficacy. To date that are 8 FDA approved ADC drugs all for oncology application using small molecule drugs. Although these ADCs with small molecules […]

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Responsive polymer-based sensing system for COVID-19 infection

Monitoring hormone levels in saliva can be used to assess female reproductive health, which can yield many benefits to individuals. For example, those that have fertility issues can use hormone levels in saliva to improve their chances of conception, while the monitoring hormone levels over time could also be used to track and help treat […]

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Computational Modelling of Cannabidiol Fluorination

Cannabidiol, is a non-intoxicating cannabinoid has anecdotal and preliminary evidence as a treatment for pain, anxiety, nausea and seizures. This project aims to identify the configuration of CBD when bound in the brain. We will use established computational techniques that have not been applied to CBD binding to calculate the pose that CBD adopts when […]

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Portable COVID-19 diagnostic system using saliva sample

This project aims to develop an easy-to-use and cost-effective saliva test, fitted for COVID-19 diagnosis and surveillance via multiplexed detection of SARS-CoV-2 viruses, COVID-19 specific antibodies immunoglobulin M and immunoglobulin G within 15 minutes. The supported intern will join a team, consists of researchers at the University of Waterloo and personnel from the partner organization, […]

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Development of Advanced Graphene-Based Antiviral Nanocomposites against COVID-19

The outbreak of the coronavirus disease (COVID-19) is a serious threat to humanity worldwide. It is known that COVID-19 is a respiratory infection, which can be transmitted from person to person via small aerosolized droplets. The goal of this project is to develop advanced functional graphene-based nanocomposites with robust antiviral and antibacterial activities. The graphene-based […]

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