Innovations Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

13270 Completed Projects

1072
AB
2795
BC
430
MB
106
NF
348
SK
4184
ON
2671
QC
43
PE
209
NB
474
NS

Projects by Category

10%
Computer science
9%
Engineering
1%
Engineering - biomedical
4%
Engineering - chemical / biological

Immune modulation with checkpoint inhibitor antibodies targeting GITR or OX40 to improve cancer immune therapy with DepoVaxTM vaccine and metronomic cyclophosphamide

Immunovaccine Inc. is developing immune therapies for cancer using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation provides controlled and prolonged exposure of antigens and adjuvants to the immune system, resulting in a strong, specific and sustained immune response. Immunovaccine’s translational research team is focused on improving responses in advanced cancers by combining DepoVax based vaccines with novel immune modulators in order to improve clinical trial design. We have previously demonstrated that metronomic cyclophosphamide in combination with DepoVax vaccination increases CD8+ T cell responses in tumor bearing mice, and results were recapitulated in human clinical studies. In this project, DepoVax will be evaluated in combination with agonist antibodies towards the checkpoint molecules GITR and OX40 which are primarily expressed on T cells and are reported to enhance their activity. We will also evaluate combining DepoVax with a histamine antagonist that has reported to reduce immune suppressive cells induced by tumors. The results of this study will help to identify the best combinatorial treatments Immunovaccine should pursue in clinical testing.

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Faculty Supervisor:

Jean Marshall

Student:

Ava Vila-Leahey

Partner:

Immunovaccine Inc.

Discipline:

Biology

Sector:

Life sciences

University:

Dalhousie University

Program:

Accelerate

Segment-based Fleet Management System for Semi Real-Time Analysis

Traditional fleet management systems suffer from zone-based aggregation. i.e. they use aggregate zone-level road and terrain characteristics to estimate trip performance indicators. In addition, most of these systems require intermediate ad-hoc staging tables to generate trip performance reports. To address these limitations, this research aims at developing a segment-based fleet management system for near real-time analysis. The proposed approach uses static segmentation to associate road and terrain characteristics with each segment of the road network. Then dynamic segmentation is utilized to aggregate and link event data to road and terrain characteristics at the segment- and trip-levels. This treatment ensures more accurate analysis at a lower computational cost, without the need for intermediate staging tables specific to a particular report. In addition, optimal travel routes can be generated to minimize cost, minimize slope, maximize speed, etc. to the destination or to the nearest city or highway from a given road segment.

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Faculty Supervisor:

Ahmed Idris

Student:

Abdul Rahman Masoud

Partner:

Streamline Transportation Technologies Inc

Discipline:

Engineering

Sector:

Automotive and transportation

University:

University of British Columbia Okanagan

Program:

Accelerate

Controlling microbial processes in fracing fluids

Unconventional gas reservoirs are a great energy resource in the province of BC and Alberta and thus for Canada in general. Extracting this resource is not as straight forward as conventional gas reservoirs and requires hydraulic fracturing, also known as fracing or fracking, which has recently become a controversial topic in the public eye. This research project will examine water and fluids used in and returning from frac operations with respect to its geochemistry and bacterial populations. By knowing how bacterial population change geochemical parameters we can improve the effectiveness of the fracing and lower its environmental impact. The results of this research may therefore make fracing economically more feasible and safer for the environment.

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Faculty Supervisor:

Sean Crowe

Student:

Yakenalem Abebe

Partner:

Shell Canada

Discipline:

Engineering

Sector:

Oil and gas

University:

University of British Columbia

Program:

Accelerate

One-Way Degassing Valve Design, Function and Application in Coffee Packaging

The purpose of this study is to gather information relating to the one-way degassing valves used within the coffee industry in order to improve upon current designs. This will be achieved through studying the opening/closing properties of commercial valves, as well as using a model system to elucidate the effects of valve components on these properties, as a function of pressure, rate of pressure change, and temperature. The study will also investigate flow behavior of different food grade sealing fluids within the model valve system, as a function of pressure and temperature. Finally, the study seeks to analyze the overall effectiveness of the degassing valve in maintaining coffee quality in selected packaging systems. This will involve measurement of select volatile compounds, freshness measures, found within the headspace of the coffee, then correlating/validating these measures to consumer acceptance through sensory evaluation.

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Faculty Supervisor:

Loong Tak Lim

Student:

Jessey Cowell

Partner:

O2i Ltd

Discipline:

Food science

Sector:

Agriculture

University:

University of Guelph

Program:

Accelerate

Advancing Visualization for Mobile E-Commerce Clickstream Data

We propose to design and build an advanced visual analytics tool to support the analysis of large-scale e-commerce datasets. This data is generated by software platforms that collect information about the performance of e-commerce systems, consumer behaviour, and messages sent by retailers to consumers. Current e-commerce tools provide only simple overview statistics because of the scale and complexity of this data, but more sophisticated analysis could lead to much more effective strategies for e-commerce engagement. Our new system will help data analysts drill down into this dense sea of data and discover successful patterns or understand previously unknown obstacles to customer satisfaction. Insights received from using the tool will help our industrial partner Mobify make vital decisions towards the growth and improvement of their e-commerce platform, and our own insights from observing how the tools is used will feed back into improved design guidelines for the visualization research community.

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Faculty Supervisor:

Tamara Munzner

Student:

Kimberly Dextras-Romagnino

Partner:

Mobify Research and Development Inc

Discipline:

Computer science

Sector:

Information and communications technologies

University:

University of British Columbia

Program:

Accelerate

Utilization of Supersolidus Liquid Phase Sintering (SLPS) in Metal Injection Molding (MIM) for Superalloys in aerospace applications

Powder metallurgy uses metal powders to produce parts of varying complexity. The processes can generally be divided in two big steps. The first is to form the powder into the required shape. This is generally done by pressing or molding the powder. The second step is to consolidate the powder into a solid piece of metal. This is done by heating the formed powder just below its melting temperature. At this point the metal particles will slowly coalesce into a uniform metal structure. This however does not work very well with all metal powder, in particular with metals that are designed to be very resistant at high temperature. This project will explore the possibility of going slightly above the melting temperature so that a small amount of liquid will form to help in the merging of the powder particles. More specifically we will explore this technique using industrial equipment and the metal injection molding (MIM) process at P&WC. This fundamental research will permit P&WC to evaluate the viability of this process for future production incorporation.

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Faculty Supervisor:

Stephen Corbin

Student:

Addison Rayner

Partner:

Pratt & Whitney Canada

Discipline:

Engineering

Sector:

Aerospace and defense

University:

Dalhousie University

Program:

Accelerate

Oil and lipid improvements in field pea to develop a non-traditional oilseedcrop

It has been noted in recent studies that provided an increase in the lipid content of the field pea (Pisum Sativum L.) through genetic manipulation, it can be used as a viable commercial alternative to conventional oilseed crops, which include canola and soybean. Genetic transformants with high lipid content can be created in the McGill University laboratories but its commercial viability needs to be tested with an industry partner. For this purpose, this research proposal aims to accelerate the commercial deployment of an oilseed pea through industrial field-testing with Agrocentre Belcan to identify natural variations created by genetic modifications and creating a business model that will lead to a profitable commercial venture for the company, if it were to act as a commercial vendor for the oilseed pea.

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Faculty Supervisor:

Mark Lefsrud

Student:

Philip Ossowski

Partner:

Agrocentre Belcan

Discipline:

Engineering

Sector:

Energy

University:

McGill University

Program:

Accelerate

Models, algorithms and technologies for the treatment of atrial fibrillation caused by heart blockages

Heart failure is among the causes of death in developed countries. Scientific and medical research has made improvements in treating this condition. Mathematical modelling and computer simulation would help in developing the necessary technologies to detect and treat heart blockages and also give a better understanding and protocols for ablation, the clinical procedure used to treat this condition. This research aims to extend the application of the existing mathematical models and simulation techniques for the electrical activity of the heart associated with blockages as well as their treatment via catheter ablation. Also, in a close collaboration with Appairy Supercomputing, we will generate and implement the algorithms and software to perform these simulations. The results of this research will help Appairy’s technology in designing and improving their Medical Diagnostic Applications.

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Faculty Supervisor:

Raymond Spiteri

Student:

Jessica Cervi

Partner:

Appairy Supercomputing

Discipline:

Computer science

Sector:

Information and communications technologies

University:

University of Saskatchewan

Program:

Accelerate

Statistical and Physiological Beat Modelling of Seismocardiogram Signal

“Seismocardiogram (SCG) is a signal that is captured by placing an accelerometer on the human chest. This signal captures very important timing information such as opening and closing of the heart valves. In addition to these timing information, the non-invasive nature of this signal makes it an attractive solution for remote monitoring of patients with heart conditions.
The morphology of SCG signal changes depending on different types of heart conditions and diseases. A mathematical model represents the morphology of a signal in terms of certain parameters. The hypothesis is that different signal morphologies could be represented by different set of parameters. The ultimate goal of this project is design and implementation of a model that captures the morphology of SCG signal. Heart force medical is producing medical devices that incorporates SCG for diagnosis/monitoring of patients. The company could utilize the implementation of such model on their devices.”

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Faculty Supervisor:

David Campbell

Student:

Farzad Khosrow-khavar

Partner:

Heart Force Medical Inc.

Discipline:

Engineering

Sector:

Medical devices

University:

Simon Fraser University

Program:

Elevate

Assessing the validity of virtual simulation as a learning tool in the medical field.

With the increasing prevalence of mobile devices, it is unsurprising that they are also being adapted for use as tools for learning and perfecting complex procedures. One of these uses is training health care providers through simulated medical procedures. Two important points should be considered when designing simulated systems to assess the efficacy and efficiency of these teaching tools. 1) Individual differences in emotional biases and learning profiles may necessitate personalized stimulus presentations within simulated environments to achieve optimal and translatable learning. 2) Learning through indirect simulation, while beneficial to acquiring conceptual understanding of a procedure, may not utilize the same neural systems as actual performance of the actions. By utilizing cutting edge neuroimaging techniques, we will help optimize teaching performance by ensuring that the neurocognitive pathways trained in the simulated procedures are indeed the same pathways utilized in real-world application.

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Faculty Supervisor:

Rebecca Todd

Student:

James Kryklywy

Partner:

Conquer Mobile

Discipline:

Psychology

Sector:

Medical devices

University:

University of British Columbia

Program:

Elevate

Implementation and Evaluation of an Integrated Chiropractic Service for Musculoskeletal Conditions into the Canadian Forces Health Service

Low back pain is a leading cause of disability worldwide. The Canadian Armed Forces (CF) has a greater incidence of LBP than the general population. LBP is responsible for a large proportion of medical releases in the CF with many cases resulting in lifelong pain and disability. Improved early access to evidence-based care could help prevent chronicity and recurrences, and reduce health care costs. The purpose of this project is to implement and evaluate a new inter-disciplinary, patient-centred health care service that includes chiropractic services for the management of LBP in the CF. The main outcomes are clinical (e.g., level of pain and function), and return to duty of CF members who require care for LBP. If successful, the partner organizations would benefit in fulfilling their mission to serve their members and the public by advancing the understanding and use of chiropractic care.

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Faculty Supervisor:

Pierre Cote

Student:

Carol Cancelliere

Partner:

University of Ontario Institute of Technology

Discipline:

Kinesiology

Sector:

Medical devices

University:

Ontario Tech University

Program:

Elevate

The use of inertial measurement units to quantify sport-specific movement patterns in elite sprint kayak athletes

Canoe kayak athletes use difficult body movements to move their boats at fast speeds. It has been hard to measure body movements that are needed to win paddling races in the past. Wearable devices are now able to measure athlete’s body movements when they are paddling. The goal of this research is to learn new ways to give athletes information about their movements so they can be better at their sport. The intern will learn how to use the wearable devices to help the athlete’s become faster paddlers. The intern will also work with a group of partners that will help grow the intern’s sport science abilities. Canoe Kayak Canada and Own The Podium are using this research to help athletes win medals for Canada at future Olympics and Paralympics.

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Faculty Supervisor:

Janie Wilson

Student:

Joshua Goreham

Partner:

Canoe Kayak Canada

Discipline:

Engineering - biomedical

Sector:

Life sciences

University:

Dalhousie University

Program:

Accelerate

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