CyTOF-based characterization and isolation of MDSC subsets

Myeloid-derived suppressor cells (MDSC) are an unusual type of blood cell that is able to potently turn off immune responses. These cells are not normally present in healthy individuals, when a tumour is present, MDSC can block clearance of the tumour by the body’s immune defenses. A better understanding of how MDSC shut down tumour clearance would greatly improve the success of cancer treatments. Unfortunately, MDSC are difficult for scientists to study because there is currently no effective method to isolate them in pure form.

Wearable Sensors for Monitoring of Human Activities

Quantification of human standing balance provides unique insight into the integrity of the human sensorimotor system, including the identification of balance deficits in conditions such as mild traumatic brain injury (mTBI), stroke, and aging. While a number of high-cost instrumented balance quantification systems are available, they are primarily geared towards research settings. Novel technologies using accelerometry or other inexpensive sensors are being developed for use in the clinical markets.

Investigation of turbulent three-phase flows in the FLSmidth nextSTEPTM flotation cells using CFD-PBM-kinetic simulation framework

The proposed research is aimed at both understanding and improving the flotation equipment design through the development and application of comprehensive multiphysics platform, which has the potential to create more accurate, fundamental basis for modeling, optimization, and scale-up of industrial flotation processes, based on physics rather than empirics and intuition.

Level the field: sport and disability inclusion

Canadian Sport Policy states a desire to provide sport programs that are accessible and reflect the full diversity of Canadian society. However a recent evaluation of 61 sport organizations in British Columbia revealed that most organizations are ill-equipped to serve people with disabilities wishing to partake in their leisure and sport programs (with some individuals with specific types of disabilities and impairments having little to no opportunity to get involved).

Investigation of turbulent three-phase flows in the FLSmidth nextSTEPTM flotation cells using CFD-PBM-kinetic simulation framework

The proposed research is aimed at both understanding and improving the flotation equipment design through the development and application of comprehensive multiphysics platform, which has the potential to create more accurate, fundamental basis for modeling, optimization, and scale-up of industrial flotation processes, based on physics rather than empirics and intuition.

The Effective Knowledge Transfer of Novel Approaches to Understanding and Addressing the Risk Factors for Cognitive Fatigue in Wildland Firefighting Settings

Given the increased risk to fatigue in fire zone dispatchers working in wildland fire settings, and the lack of scientific literature about this topic, the purpose of this study is to create evidence-based knowledge translation tools to help address and reduce the risks for cognitive fatigue and poor decision making in wildland firefighting settings. These materials will be originated based on an onsite investigation to further understand the complex relationship and mechanisms of fatigue in coordinator staff during a typical fire season.

Tree to Home Scoping

This research aims to identify the challenges and opportunities that exist within and amongst First Nations communities for creating culturally appropriate and resilient housing models and local economies. It will build understanding around what is required to transform the current housing system from one that uses external labour, resources and businesses to one that promotes local livelihoods, value-added businesses and local resource use within a First Nations culturally focused bioregional economy.

Development of a continuous fluidized bed biomass torrefaction technology

There have been great interests on the utilization of biomass as a potentially renewable and sustainable energy source for greenhouse gas mitigation. In British Columbia and Quebec, abundantly available biomass residues are potential renewable energy sources if effectively utilized.

Cognitive and well-being impacts of tunable LED lighting in secondary school students

The current project aims to examine how tunable LED lighting influences productivity and well-being in students at the Port Coquitlam’s Riverside secondary school. The project aims to identify the optimal lighting conditions in order to maximize productivity and well-being in healthy students as well as students with special needs. We hypothesize that the tunable LED lighting that is consistent with the natural daylight cycle will be more beneficial to students than standard constant lighting condition in an average classroom.

Investigating Ecosystem Change in British Columbia’s Coastal Habitats

Nearshore marine ecosystems are undergoing change, with ecological, economical and cultural ramifications. Yet, we lack empirical understanding and observation of the nature of this change, over long periods of time and across continental coastlines. Additionally, the drivers of change in coastal systems are numerous: climatic forcing, predator recovery, and development of foreshore areas, amongst others. As such, deciphering the agents of change remains challenging.

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