Development of an Integral Strategy for Model-based Dose Adaptation in Chemotherapy

The overall objective of this PDF project is to propose an integrated dose adaptation strategy that can be used in anticancer drug treatment. Indeed, many chemo agents used to treat tumors often induce dangerous side effects or toxicity, such as neutropenia [Crawford et al.] and hand-foot syndrome [Janusch et al.]. Since some tumors can only be destroyed by sufficiently high doses of chemotherapeutic agents, these harmful and lethal toxicities have become a main obstacle that limit the full use of the dosage of anticancer drugs or even force the discontinuation of chemo treatment.

Études numériques de la diffusion ionique dans les cathodes pour piles de nouvellegénération au magnésium et au sodium

Objectifs

Le projet proposé en collaboration entre l'Université de Montréal et l'Institut de Recherche d'Hydro-Québec (IREQ) vise à accélérer le développement et la commercialisation de piles rechargeables basées sur le magnésium et le sodium en améliorant notre compréhension fondamentale et théorique des enjeux associés avec cette technologie. Les objectifs concrets du projet sont

• améliorer la compréhension des processus de diffusion au sein de certaines cathodes prometteuses pour application dans des piles d'intercalation au magnésium et au sodium,

Improving radiation oncology treatment planning using dual-energy computed tomography

Dual-energy computed tomography (DECT) is a new technology that was introduced in radiology departments in the last few years. At CHUM, in collaboration with Siemens, we installed a DECT in the radiation oncology department. The global objective of this project is to develop and confirm the various applications of DECT in radiation oncology. Specifically, a first objective is to assess the improved accuracy in radiation dose calculation needed for treatment planning.

Importance clinique de pathogènes entériques dans la diarrhée péri-sevrage des porcelets et impact sur la contamination des carcasses par des pathogènes alimentaires

Parmi les différentes étapes de production, le sevrage des porcelets est un moment crucial ayant un impact important sur la productivité et la rentabilité des entreprises. Cette période représente en effet un risque élevée pour la transmission de maladies infectieuses à cause du stress qu’elle engendre et à cause de l'immaturité du système immunitaire au cours des premières semaines de vie. Les cas de diarrhées peuvent rapidement prendre des proportions épidémiques et avoir des conséquences dramatiques à l’échelle du troupeau.

Etiology, prevention and rehabilitation of shoulder injuries in elite swimmers and waterpolo players: a longitudinal study

Chronic shoulder injuries are common in athletes competing in overhead sports such as waterpolo, swimming and synchronized swimming. These injuries are costly both financially and in terms of performance to the athletes and sport organizations. The purpose of this project is to create new sport-specific clinical and functional assessment protocols and to improve training strategies for shoulder injury prevention and elite sport performance.

Predicting job performance through personality testing: Improving the quality of research and practice at a Human Resources Consulting Firm

The Pathfinder Career System is a sophisticated psychological assessment tool that provides a high-definition portrait of an individual’s behavioural profile that focuses on the key attributes required for success in a specific job position. The purpose of this project is for Optimum Talent inc., a Human Resources Consulting firm, to be in a position to make optimal use of the test, by determining how it can be integrated into the current services offered by the firm and by pushing the tool further to respond to very specific client demands.

Development of a gender-sensitive organizational assessment model

The objective of this assignment is to strengthen the institutional and organizational assessment (IOA) model developed by Universalia to identify gender dimensions which affect equity and performance within an organization. To do so, the intern will be asked to proceed to a mapping of existing gender equality tools (as well as their strengths and weaknesses) used in the assessment and capacity-building of international development organizations in order to further develop the IOA model.

Development of a gender-sensitive organizational assessment model

The objective of this assignment is to strengthen the institutional and organizational assessment (IOA) model developed by Universalia to identify gender dimensions which affect equity and performance within an organization. To do so, the intern will be asked to proceed to a mapping of existing gender equality tools (as well as their strengths and weaknesses) used in the assessment and capacity-building of international development organizations in order to further develop the IOA model.

Pharmaceutical development of a thermo-sensitive polymer for intrabladder delivery

Targeted delivery of drugs can reduce the side effects associated with oral delivery systems. The urethra provides easy access of therapeutic agents to the urinary bladder, an ideal organ for localized therapy for the treatment of bladder cancer, interstitial cystitis, overactive bladder, and chronic prostatitis. We propose a new therapeutic approach to increase the residency time and efficacy of the drugs by using biogradable polymers as a drug carrier, allowing a prolonged release of drugs in the bladder.

Adaptation d’une modélisation statistique de l’érosion de cavitation à un autre type de turbine hydraulique et intégration d’un modèle physique

L’une des stratégies mise en oeuvre par Hydro-Québec pour accompagner la demande croissante d’électricité, consiste à caractériser les phénomènes contribuant à la dégradation des turbines hydrauliques. Dans cette optique, le phénomène de cavitation est étudié, car il est à l’origine de l’érosion et donc de l’endommagement des turbines. Ce phénomène correspond au passage de l’eau de l’état liquide à l’état gazeux sous l’effet d’une baisse de pression, engendrée par la rotation des aubes de la turbine.

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