Effectiveness of EarlyDetect, a psychiatric assessment program, using a mobile APP interface

Mental health illness cost over $50 billion in the Canadian economy annually, and is prevalent at workplace. The cost and prevalence of menial health illness can be greatly mitigated with early detection and intervention. EarlyDetect is a program developed by Chokka Center for Integrative Health for convenient, accurate and reliable self-assessment of mental illness, and has been validated in a pen-and-paper form.

Performance analytics and monitoring in ice-hockey

In professional sports, sustained performance largely depends on having the best players healthy and free of injury. Player testing and monitoring has become a key area of development for many professional teams in order to track players' health and performance. The purpose of this project is to build on the partner organization’s player monitoring program to identify key sport performance indicators and help in the team’s decision-making process.

Development of a High Power Picosecond Infrared Laser for Medical Applications

This project will focus on furthering the development of a compact picosecond infrared laser (PIRL) system for use in surgical applications. This laser system, which represents a new paradigm for laser surgery, is unique in its ability to provide high-speed cutting of biological tissue without the collateral damage to surrounding tissues inherent in current surgical laser technologies. Furthermore, this laser allows for the possibility of real-time diagnostics, as molecular fragments of the ablated tissue are left intact and can be analyzed through mass spectrometry.

Developing a new magnetic sensor for application in biosensing and surveying - Year 2

Detecting subtle chemical and physical changes occurring at the early stages of chronic disease and many other infectious diseases caused by harmful bacteria is still a challenge, as ultra-sensitive sensors with large signal-to-noise-ratio are required to detect them. We recently explored new ways to enhance the sensitivity of magnetic nano-sensors and theoretically demonstrated that under optimum design conditions, the sensitivity can be improved by up to a thousand - higher than any of the biosensors currently available on the market.

Development and Validation of Software for the Three-dimensional Quantification and Visualization of Blood Flow Hemodynamics in Patients with Aortic Insufficiency using 4D flow MRI. Year 2

The aim of this proposal is to assist in the development and validation of a dedicated 4D flow MRI analysis software for the evaluation of aortic valve insufficiency. Before being commercialized this software requires validation considering the large amount of data required to be pre-processed (over 2,000 files per case), elemental data corrections, data analysis preparation, data analysis algorithms, and 3D visualization.

HAT TRICK: An innovative health promotion program for men

Despite the benefits associated with staying physically active and eating a healthy diet, men are less likely than women to engage in these behaviours. Healthy lifestyle programs that are offered in collaboration with professional sport teams have been found to engage men in being more active and eating healthier. HAT TRICK was designed to specifically target men and is being offered with major junior ice hockey teams in the Canadian Hockey League (CHL).

Developing a microfluidic lung-on-a-chip model for accelerating the discovery of novel therapeutic targets for Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. There is a pressing need to discover novel targets to enable precision health, promote new therapeutic discoveries, and ultimately improve the care and health outcomes of patients with COPD. However, this process is hindered by the use of outdated cell culture systems and animal models.

From the ParticipACTION Physical Activity Report Card to the Global Matrix 3.0: Impact Evaluation and Strategy Development

Internationally, physical activity levels among children and youth are declining, while sedentary behaviours are increasing, leading to the global rise in non-communicable disease. This project aims to contribute to childhood physical activity promotion in Canada and worldwide, and to the international diffusion of scientific knowledge concerning childhood physical activity though three actions: 1. the evaluation of the impact of the ParticipACTION Report Cards since 2014; 2. the optimization of the development of the Global Matrix 3.0; and, 3.

Salivary insulin profiles throughout the day in healthy humans

The hormone insulin rises in the blood after consuming food. Too high of an insulin response may be a sign of dysfunctional metabolism and has also been shown to promote weight gain. Thus, if insulin levels rise too high after a meal it may indicate that someone is metabolically unhealthy or is prone to obesity. Currently insulin is only measured in research studies using blood samples and costly, time consuming measurement techniques. This project aims to determine if saliva can be used to measure insulin in order to allow for non-invasive insulin measurement.

Evaluation Capacity Network: Aligning Evaluative Thinking and Practice among Early Childhood Stakeholders

This project aims to provide evidence and research support to BGCBigs in the implementation of their Building an Evaluation Framework and Capacity for Sustainability project. BGCBigs recognizes that achieving their goal of ‘supporting our children and youth on the path to success’ depends upon an organization committed to evaluative thinking, learning and utilization of evidence for decision-making. This project will enable BGCBigs to conduct quality evaluations and use evidence to improve programs for children and youth.

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