Enhancement of signal quality in Near Infra-Red (NIR) spontaneous Raman spectroscopy using coherent detection techniques for use in real-time cancer microsurgeries

Raman spectroscopy is a compound identification technique that can be used for real-time identification of cancerous tissues during surgery. The development and clinical translation of an intraoperative surgical-guidance instrument based on this technique is the main objective of ODS Medical, a Canadian startup. However, Raman signals are intrinsically very weak thereby requiring the measurements to be done in an absolute dark environment in order to minimize interferences by sources of light in the operating room.