his study focuses on the postnatal histomorphology of developing organs in mice and rabbits and compares the key events between human and experimental species (mice and rabbits). It will provide an essential resource for nonclinical safety evaluations of pediatric drugs and will be helpful in preparing appropriate study designs and testing strategies. Neonatal and juvenile organs greatly differ morphologically and functionnally from adult animals.
The project is designed with the following objectives: Improving the statistical formulation for the recently developed stock assessment model for BC lakes so that it maybe fitted to more types of field data, e.g., stocking, gillnet test fishing and angling effort data, and applying it toimprove understanding of kokanee-rainbow trout interactions in lakes, assembling lake characteristics informationand quantifying the biological potential for kokanee production in BC stocked lakes, analysing creel informationand angler effort data to explore angler preferences across BC for targeted specie
Research objectives: 1. Assess the incorporation of PUFAs in offspring's blood and brain tissue following maternal AM supplementation 2. Investigate the effect of maternal AM supplementation on the offspring's antibody-mediated (AbMIR) and cellmediated (CMIR) immune responses 3.
In cattle, energy requirements after parturition increase exponentially, primarily, due to increase in milk production. Negative energy balance hampers reproductive efficiency, inflicting heavy economic losses to dairy industry. Poor reproduction is the most important cause of culling dairy cows. Feed supplementation with vitamins improves energy balance. Also, observations in humans indicate that folic acid and vitamin B12 improve oocyte quality and pregnancy establishment.
Parmi les différentes étapes de production, le sevrage des porcelets est un moment crucial ayant un impact important sur la productivité et la rentabilité des entreprises. Cette période représente en effet un risque élevée pour la transmission de maladies infectieuses à cause du stress qu’elle engendre et à cause de l'immaturité du système immunitaire au cours des premières semaines de vie. Les cas de diarrhées peuvent rapidement prendre des proportions épidémiques et avoir des conséquences dramatiques à l’échelle du troupeau.
In dairy cows, future generations are created by embryo transfer techniques, which entail a superovulation treatment followed by fertilization in the field or in the laboratory. Due to enormous pressure exerted by breeders, cows are now superovulated very young, even before puberty and thereafter are superovulated routinely. Despite improvements in this technique, there is still variability in the ovarian response to treatment and loss of ovarian response after the 5th or 6th superovulation treatment.
Streptococcus suis is one of the most important causes of bacterial disease in post-weaned piglets. Affected animals suffer from meningitis (affected brain), endocarditis (affected heart), arthritis (affected joints) and septicemia (general infection). There are 35 serotypes of S. suis (same bacteria but different antigens). Some of these serotypes (such as serotype 2) can also affect humans (transmission from pigs), causing serious disease. Usually, veterinarians use antibiotics to treat and even protect animals.
The profitability of dairy production is based on the ability of the animal to have high milk production, good health and good fertility. A major challenge for dairy producers is to select for high performing animals and avoid the undesirable correlated response between production and other traits.
The sea louse (Lepeophtheirus salmonis) is the most economically important parasite that affects salmon farming and it is a cause for major environmental concern due to the risk of transmission to wild salmon population. The development of drug resistance in a number of L. salmonis populations to the most effective sea lice therapy - SLICETM diminishes the ability to control sea lice levels on farmed salmon.
Since yeast probiotics and their cell wall components (CWC) are being used to treat enteric inflammatory diseases in different species including humans, they may be useful for preventing Johne’s disease, a chronic inflammatory bowel disease of ruminants caused by Mycobacterium avium spp. paratuberculosis (MAP). Considerable variation in the efficacy of different yeast probiotics and their CWC has been reported; therefore we are proposing to develop in vitro assays that will allow us to assess potential anti-adhesive properties of yeast strains and CWC using MAP as a target pathogen.